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Percutaneous transluminal angioplasty and stenting (PTAS) in patients with symptomatic intracranial vertebrobasilar artery stenosis (IVBS)

Ramtin Pourahmad, Kiarash Saleki, Sina Zoghi, Ramtin Hajibeygi, Hamed Ghorani, Amin Javanbakht, Sina Goodarzi, Parsa Alijanizadeh, Kelly Trinh, Ravi Shastri, Mohammad Ghasemi-Rad
DOI: 10.1136/svn-2024-003224 Published 21 August 2024
Ramtin Pourahmad
1Tehran University of Medical Sciences, Tehran, Iran (the Islamic Republic of)
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Kiarash Saleki
2Student Research Committee, Babol University of Medical Science, Babol, Iran (the Islamic Republic of)
3USERN Office, Babol University of Medical Sciences, Babol, Iran
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Sina Zoghi
4Shiraz Medical School, Shiraz, Iran (the Islamic Republic of)
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  • ORCID record for Sina Zoghi
Ramtin Hajibeygi
1Tehran University of Medical Sciences, Tehran, Iran (the Islamic Republic of)
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Hamed Ghorani
1Tehran University of Medical Sciences, Tehran, Iran (the Islamic Republic of)
5Advanced Diagnostic and Interventional Radiology Research Center(ADIR), Tehran University of Medical Science, Tehran, Iran
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Amin Javanbakht
6Abadan University of Medical Sciences, Abadan, Iran (the Islamic Republic of)
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Sina Goodarzi
7Student Research Committee, Lorestan University of Medical Sciences, Khorramabad, Iran (the Islamic Republic of)
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Parsa Alijanizadeh
2Student Research Committee, Babol University of Medical Science, Babol, Iran (the Islamic Republic of)
3USERN Office, Babol University of Medical Sciences, Babol, Iran
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Kelly Trinh
8Texas Tech University Health Sciences Center, Lubbock, Texas, USA
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Ravi Shastri
9Department of radiology, Section of Vascular Interventional Radiology, Baylor College of Medicine, Houston, Texas, USA
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Mohammad Ghasemi-Rad
9Department of radiology, Section of Vascular Interventional Radiology, Baylor College of Medicine, Houston, Texas, USA
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  • ORCID record for Mohammad Ghasemi-Rad
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  • Figure 1
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    Figure 1

    Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020 flow diagram for new systematic reviews which included searches of databases and registers only. *Consider, if feasible to do so, reporting the number of records identified from each database or register searched (rather than the total number across all databases/registers). **If automation tools were used, indicate how many records were excluded by a human and how many were excluded by automation tools.

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    Figure 2

    Mechanism of different medications inhibiting the neointimal hyperplasia.

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  • Table 1

    Summary of basic characteristics and outcomes

    CharacteristicsValue
    Cohort size (n)1928
    Demographics
     Age (years), mean (SD) (n=1889)63.4±NA
     Gender (male) (n=1889)1490 (78.87%)
    Risk factors
     Hypertension (n=1657)1332 (80.39%)
     Diabetes mellitus (n=1657)579 (34.94%)
     Coronary artery disease (n=706)162 (22.95%)
     Dyslipidaemia (n=1375)742 (53.96%)
     Tobacco smoking (n=1630)811 (49.75%)
    Outcome
     Mean time from onset symptom to recanalisation day (n=1139)21.188±NA
     Procedure stroke/TIA rates (n=64)9 (14.06%)
     Periprocedural stroke rate and death from any cause (within 30 days of treatment) (n=891)63 (7.07%)
     Mean follow-up (months) (n=1928)18.96±NA
     Rate of stroke/TIA during clinical follow-up period (n=1398)108 (7.73%)
     Rate of restenosis (>50%) during follow-up (n=1059)102 (9.63%)
     Mortality (n=1090)51 (4.68%)
    Studies quality (n=31)
     Good16 (51.61%)
     Fair13 (41.93%)
     Poor2 (6.45%)
    • NA, not applicable; TIA, transient ischaemic attack.

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    [svn-2024-003224supp001.pdf]

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    This web only file has been produced by the BMJ Publishing Group from an electronic file supplied by the author(s) and has not been edited for content.

    • Data supplement 1
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Stroke and Vascular Neurology: 10 (1)
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Percutaneous transluminal angioplasty and stenting (PTAS) in patients with symptomatic intracranial vertebrobasilar artery stenosis (IVBS)
Ramtin Pourahmad, Kiarash Saleki, Sina Zoghi, Ramtin Hajibeygi, Hamed Ghorani, Amin Javanbakht, Sina Goodarzi, Parsa Alijanizadeh, Kelly Trinh, Ravi Shastri, Mohammad Ghasemi-Rad
Stroke and Vascular Neurology Aug 2024, svn-2024-003224; DOI: 10.1136/svn-2024-003224

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Percutaneous transluminal angioplasty and stenting (PTAS) in patients with symptomatic intracranial vertebrobasilar artery stenosis (IVBS)
Ramtin Pourahmad, Kiarash Saleki, Sina Zoghi, Ramtin Hajibeygi, Hamed Ghorani, Amin Javanbakht, Sina Goodarzi, Parsa Alijanizadeh, Kelly Trinh, Ravi Shastri, Mohammad Ghasemi-Rad
Stroke and Vascular Neurology Aug 2024, svn-2024-003224; DOI: 10.1136/svn-2024-003224
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Percutaneous transluminal angioplasty and stenting (PTAS) in patients with symptomatic intracranial vertebrobasilar artery stenosis (IVBS)
Ramtin Pourahmad, Kiarash Saleki, Sina Zoghi, Ramtin Hajibeygi, Hamed Ghorani, Amin Javanbakht, Sina Goodarzi, Parsa Alijanizadeh, Kelly Trinh, Ravi Shastri, Mohammad Ghasemi-Rad
Stroke and Vascular Neurology Aug 2024, svn-2024-003224; DOI: 10.1136/svn-2024-003224
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