Skip to main content

Main menu

  • Online first
    • Online first
  • Current issue
    • Current issue
  • Archive
    • Archive
  • Submit a paper
    • Online submission site
    • Instructions for authors
  • About the journal
    • About the journal
    • Editorial board
    • Instructions for authors
    • FAQs
    • Chinese Stroke Association
  • Help
    • Contact us
    • Feedback form
    • Reprints
    • Permissions
    • Advertising
  • BMJ Journals

User menu

  • Login

Search

  • Advanced search
  • BMJ Journals
  • Login
  • Facebook
  • Twitter
Stroke and Vascular Neurology

Advanced Search

  • Online first
    • Online first
  • Current issue
    • Current issue
  • Archive
    • Archive
  • Submit a paper
    • Online submission site
    • Instructions for authors
  • About the journal
    • About the journal
    • Editorial board
    • Instructions for authors
    • FAQs
    • Chinese Stroke Association
  • Help
    • Contact us
    • Feedback form
    • Reprints
    • Permissions
    • Advertising
Open Access

Phase II randomised, double-blind, placebo-controlled trial to assess the efficacy and safety of MLC1501 in patients with stroke: the MLC1501 study Assessing Efficacy in post-STrOke Subjects with mOtor deficits (MAESTOSO) study protocol

Christopher P L H Chen, Romulo U Esagunde, Cyrus G Escabillas, John Harold Hiyadan, Joel M Advincula, Christian Oliver C Co, Maria Epifania V Collantes, Annabelle Y Lao, Yeow-Hoay Koh, Deidre Anne De Silva, Carol Huilian Tham, Johnny K Lokin, Narayanaswamy Venketasubramanian
DOI: 10.1136/svn-2024-003750 Published 6 February 2025
Christopher P L H Chen
1National University of Singapore, Singapore
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Christopher P L H Chen
Romulo U Esagunde
2Jose R Reyes Memorial Medical Center, Manila, Philippines
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Cyrus G Escabillas
2Jose R Reyes Memorial Medical Center, Manila, Philippines
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
John Harold Hiyadan
3Baguio General Hospital and Medical Center, Baguio, Philippines
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Joel M Advincula
4West Visayas State University Medical Center, Iloilo City, Philippines
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Christian Oliver C Co
5Quirino Memorial Medical Center, Quezon City, Philippines
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Christian Oliver C Co
Maria Epifania V Collantes
6Manila Doctors Hospital, Manila, Philippines
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Annabelle Y Lao
7Southern Philippines Medical Center, Davao City, Philippines
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Yeow-Hoay Koh
8Changi General Hospital, Singapore
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Deidre Anne De Silva
9National Neuroscience Institute–Singapore General Hospital Campus, Singapore
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Carol Huilian Tham
10National Neuroscience Institute–Tan Tock Seng Campus, Singapore
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Johnny K Lokin
11University of Santo Tomas Hospital, Manila, Philippines
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Narayanaswamy Venketasubramanian
12Raffles Hospital, Singapore
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • eLetters
  • Info & Metrics
  • PDF
Loading

Article Information

DOI 
https://doi.org/10.1136/svn-2024-003750
PubMed 
39915229

Print ISSN 
2059-8688
Online ISSN 
2059-8696
History 
  • Received September 25, 2024
  • Accepted January 23, 2025
  • Published online February 6, 2025.

Copyright & Usage 
© Author(s) (or their employer(s)) 2025. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ Group. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

Author Information

  1. Christopher P L H Chen1,
  2. Romulo U Esagunde2,
  3. Cyrus G Escabillas2,
  4. John Harold Hiyadan3,
  5. Joel M Advincula4,
  6. Christian Oliver C Co5,
  7. Maria Epifania V Collantes6,
  8. Annabelle Y Lao7,
  9. Yeow-Hoay Koh8,
  10. Deidre Anne De Silva9,
  11. Carol Huilian Tham10,
  12. Johnny K Lokin11,
  13. Narayanaswamy Venketasubramanian12
  1. 1National University of Singapore, Singapore
  2. 2Jose R Reyes Memorial Medical Center, Manila, Philippines
  3. 3Baguio General Hospital and Medical Center, Baguio, Philippines
  4. 4West Visayas State University Medical Center, Iloilo City, Philippines
  5. 5Quirino Memorial Medical Center, Quezon City, Philippines
  6. 6Manila Doctors Hospital, Manila, Philippines
  7. 7Southern Philippines Medical Center, Davao City, Philippines
  8. 8Changi General Hospital, Singapore
  9. 9National Neuroscience Institute–Singapore General Hospital Campus, Singapore
  10. 10National Neuroscience Institute–Tan Tock Seng Campus, Singapore
  11. 11University of Santo Tomas Hospital, Manila, Philippines
  12. 12Raffles Hospital, Singapore
  1. Correspondence to Dr Christopher P L H Chen; cplhchen{at}yahoo.com.sg
View Full Text

Article usage

Article usage: April 2025 to May 2025

AbstractFullPdf
Apr 20250231
May 20250220

Statistics from Altmetric.com

PreviousNext
Back to top
Vol 10 Issue 1 Table of Contents
Stroke and Vascular Neurology: 10 (1)
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author
  • Ed Board (PDF)
Email

Thank you for your interest in spreading the word on Stroke and Vascular Neurology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Phase II randomised, double-blind, placebo-controlled trial to assess the efficacy and safety of MLC1501 in patients with stroke: the MLC1501 study Assessing Efficacy in post-STrOke Subjects with mOtor deficits (MAESTOSO) study protocol
(Your Name) has sent you a message from Stroke and Vascular Neurology
(Your Name) thought you would like to see the Stroke and Vascular Neurology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Print
Alerts
Sign In to Email Alerts with your Email Address
Citation Tools
Phase II randomised, double-blind, placebo-controlled trial to assess the efficacy and safety of MLC1501 in patients with stroke: the MLC1501 study Assessing Efficacy in post-STrOke Subjects with mOtor deficits (MAESTOSO) study protocol
Christopher P L H Chen, Romulo U Esagunde, Cyrus G Escabillas, John Harold Hiyadan, Joel M Advincula, Christian Oliver C Co, Maria Epifania V Collantes, Annabelle Y Lao, Yeow-Hoay Koh, Deidre Anne De Silva, Carol Huilian Tham, Johnny K Lokin, Narayanaswamy Venketasubramanian
Stroke and Vascular Neurology Feb 2025, svn-2024-003750; DOI: 10.1136/svn-2024-003750

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Cite This
  • APA
  • Chicago
  • Endnote
  • MLA
Loading
Phase II randomised, double-blind, placebo-controlled trial to assess the efficacy and safety of MLC1501 in patients with stroke: the MLC1501 study Assessing Efficacy in post-STrOke Subjects with mOtor deficits (MAESTOSO) study protocol
Christopher P L H Chen, Romulo U Esagunde, Cyrus G Escabillas, John Harold Hiyadan, Joel M Advincula, Christian Oliver C Co, Maria Epifania V Collantes, Annabelle Y Lao, Yeow-Hoay Koh, Deidre Anne De Silva, Carol Huilian Tham, Johnny K Lokin, Narayanaswamy Venketasubramanian
Stroke and Vascular Neurology Feb 2025, svn-2024-003750; DOI: 10.1136/svn-2024-003750
Download PDF

Share
Phase II randomised, double-blind, placebo-controlled trial to assess the efficacy and safety of MLC1501 in patients with stroke: the MLC1501 study Assessing Efficacy in post-STrOke Subjects with mOtor deficits (MAESTOSO) study protocol
Christopher P L H Chen, Romulo U Esagunde, Cyrus G Escabillas, John Harold Hiyadan, Joel M Advincula, Christian Oliver C Co, Maria Epifania V Collantes, Annabelle Y Lao, Yeow-Hoay Koh, Deidre Anne De Silva, Carol Huilian Tham, Johnny K Lokin, Narayanaswamy Venketasubramanian
Stroke and Vascular Neurology Feb 2025, svn-2024-003750; DOI: 10.1136/svn-2024-003750
Reddit logo Twitter logo Facebook logo Mendeley logo
Respond to this article
  • Tweet Widget
  • Facebook Like
  • Google Plus One
  • Article
    • Abstract
    • Background
    • Trial objectives
    • Methods
    • Discussion
    • Conclusions
    • Data availability statement
    • Ethics statements
    • Footnotes
    • References
  • Figures & Data
  • eLetters
  • Info & Metrics
  • PDF

Related Articles

Cited By...

More in this TOC Section

  • Rationale and Study Design to Assess the Efficacy and Safety of Minocycline in Patients with Moderate to Severe Acute Ischaemic Stroke (EMPHASIS)
  • Role of histone deacetylases and sirtuins in the ischaemic stroke: a protocol for a systematic review and meta-analysis of animal studies
  • Efficacy and safety of Ferrous iron on the prevention of Vascular cOgnitive impaiRment among patients with cerebral Infarction/TIA (FAVORITE): rationale and design of a multicentre randomised trial
Show more Protocol

Similar Articles

 
 

CONTENT

  • Latest content
  • Current issue
  • Archive
  • eLetters
  • Sign up for email alerts
  • RSS

JOURNAL

  • About the journal
  • Editorial board
  • Recommend to librarian
  • Chinese Stroke Association

AUTHORS

  • Instructions for authors
  • Submit a paper
  • Track your article
  • Open Access at BMJ

HELP

  • Contact us
  • Reprints
  • Permissions
  • Advertising
  • Feedback form

© 2025 Chinese Stroke Association