Outcomes associated to the time to treatment with intravenous tenecteplase for acute ischaemic stroke: subgroup analysis of the TRACE-2 randomised controlled clinical trial

Shuya Li; Runqi Wangqin; Yuesong Pan; Aoming Jin; Hao Li; Lee H Schwamm; Marc Fisher; Bruce C V Campbell; Mark W Parsons; Ziran Wang; Hongguo Dai; Deyang Li; Runhui Li; Junhai Wang; David Wang; Yilong Wang; Xingquan Zhao; Zixiao Li; Huaguang Zheng; Yunyun Xiong; Xia Meng; Yongjun Wang

doi:10.1136/svn-2023-002694

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Outcomes associated to the time to treatment with intravenous tenecteplase for acute ischaemic stroke: subgroup analysis of the TRACE-2 randomised controlled clinical trial

Shuya Li, Runqi Wangqin, Yuesong Pan, Aoming Jin, Hao Li, Lee H Schwamm, Marc Fisher, Bruce C V Campbell, Mark W Parsons, Ziran Wang, Hongguo Dai, Deyang Li, Runhui Li, Junhai Wang, David Wang, Yilong Wang, Xingquan Zhao, Zixiao Li, Huaguang Zheng, Yunyun Xiong, Xia Meng, Yongjun Wang

DOI: 10.1136/svn-2023-002694 Published 30 December 2024

Shuya Li

1 Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

2 China National Clinical Research Center for Neurological Diseases, Beijing, China

3 Department of Clinical Trial Center, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

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Runqi Wangqin

4 Department of Neurology, Duke University Medical Center, Durham, NC, USA

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Yuesong Pan

1 Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

2 China National Clinical Research Center for Neurological Diseases, Beijing, China

3 Department of Clinical Trial Center, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

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Aoming Jin

1 Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

2 China National Clinical Research Center for Neurological Diseases, Beijing, China

3 Department of Clinical Trial Center, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

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Hao Li

1 Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

2 China National Clinical Research Center for Neurological Diseases, Beijing, China

3 Department of Clinical Trial Center, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

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Lee H Schwamm

5 Department of Neurology and Comprehensive Stroke Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

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Marc Fisher

6 Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA

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Bruce C V Campbell

7 Department of Medicine and Neurology, Melbourne Brain Centre at Royal Melbourne Hospital, University of Melbourne, Melbourne, Victoria, Australia

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Mark W Parsons

8 Department of Neurology, Liverpool Hospital, University of New South Wales South Western Sydney Clinical School, Sydney, New South Wales, Australia

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Ziran Wang

9 Department of Neurology, Linyi People's Hospital, Linyi, Shandong, China

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Hongguo Dai

10 Department of Neurology, Linfen Central Hospital, Linfen, China

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Deyang Li

11 Department of Neurology, Tengzhou Central People's Hospital, Tengzhou, Shandong, China

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Runhui Li

12 Central Hospital Affiliated to Shenyang Medical College, Shenyang, China

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Junhai Wang

13 Department of Neurology, General Hospital of DaTong Coal Mine Group, Datong, Shanxi, China

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David Wang

14 Department of Neurology, Petznick Stroke Center, Barrow Neurological Institute, Phoenix, Arizona, USA

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Yilong Wang

1 Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

2 China National Clinical Research Center for Neurological Diseases, Beijing, China

3 Department of Clinical Trial Center, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

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Xingquan Zhao

1 Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

2 China National Clinical Research Center for Neurological Diseases, Beijing, China

3 Department of Clinical Trial Center, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

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Zixiao Li

1 Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

2 China National Clinical Research Center for Neurological Diseases, Beijing, China

3 Department of Clinical Trial Center, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

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Huaguang Zheng

1 Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

2 China National Clinical Research Center for Neurological Diseases, Beijing, China

3 Department of Clinical Trial Center, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

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Yunyun Xiong

1 Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

2 China National Clinical Research Center for Neurological Diseases, Beijing, China

3 Department of Clinical Trial Center, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

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Xia Meng

1 Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

2 China National Clinical Research Center for Neurological Diseases, Beijing, China

3 Department of Clinical Trial Center, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

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Yongjun Wang

1 Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

2 China National Clinical Research Center for Neurological Diseases, Beijing, China

3 Department of Clinical Trial Center, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

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Outcomes associated to the time to treatment with intravenous tenecteplase for acute ischaemic stroke: subgroup analysis of the TRACE-2 randomised controlled clinical trial

Stroke and Vascular Neurology Dec 2024, 9 (6) 613-622; DOI: 10.1136/svn-2023-002694

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Outcomes associated to the time to treatment with intravenous tenecteplase for acute ischaemic stroke: subgroup analysis of the TRACE-2 randomised controlled clinical trial

Stroke and Vascular Neurology Dec 2024, 9 (6) 613-622; DOI: 10.1136/svn-2023-002694

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Outcomes associated to the time to treatment with intravenous tenecteplase for acute ischaemic stroke: subgroup analysis of the TRACE-2 randomised controlled clinical trial

Stroke and Vascular Neurology Dec 2024, 9 (6) 613-622; DOI: 10.1136/svn-2023-002694

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