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Low-intensity focused ultrasound stimulation promotes stroke recovery via astrocytic HMGB1 and CAMK2N1 in mice

Lin Qi, Cheng Wang, Lidong Deng, Jia-Ji Pan, Qian Suo, Shengju Wu, Lin Cai, Xudong Shi, Junfeng Sun, Yongting Wang, Yaohui Tang, Weibao Qiu, Guo-Yuan Yang, Jixian Wang, Zhijun Zhang
DOI: 10.1136/svn-2023-002614 Published 5 November 2024
Lin Qi
1 Shanghai Jiao Tong Affiliated Sixth People's Hospital, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, Shanghai, China
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Cheng Wang
1 Shanghai Jiao Tong Affiliated Sixth People's Hospital, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, Shanghai, China
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Lidong Deng
1 Shanghai Jiao Tong Affiliated Sixth People's Hospital, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, Shanghai, China
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Jia-Ji Pan
2 Department of Neurosurgery, Huashan Hospital, Shanghai Medical Collage, Fudan University, Shanghai, China
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Qian Suo
1 Shanghai Jiao Tong Affiliated Sixth People's Hospital, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, Shanghai, China
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Shengju Wu
1 Shanghai Jiao Tong Affiliated Sixth People's Hospital, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, Shanghai, China
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Lin Cai
3 Department of Neurosurgery, Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University, Shanghai, China
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Xudong Shi
4 Paul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Beijing, China
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Junfeng Sun
1 Shanghai Jiao Tong Affiliated Sixth People's Hospital, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, Shanghai, China
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Yongting Wang
1 Shanghai Jiao Tong Affiliated Sixth People's Hospital, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, Shanghai, China
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Yaohui Tang
1 Shanghai Jiao Tong Affiliated Sixth People's Hospital, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, Shanghai, China
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Weibao Qiu
4 Paul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Beijing, China
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Guo-Yuan Yang
5 Neuroscience and Neuroengineering Center, Shanghai Jiao Tong University School of Biomedical Engineering, Shanghai, China
6 Shanghai Jiao Tong University Medical School Affiliated Ruijin Hospital, Shanghai, China
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Jixian Wang
6 Shanghai Jiao Tong University Medical School Affiliated Ruijin Hospital, Shanghai, China
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Zhijun Zhang
1 Shanghai Jiao Tong Affiliated Sixth People's Hospital, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, Shanghai, China
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Article Information

vol. 9 no. 5 505-518
DOI 
https://doi.org/10.1136/svn-2023-002614
PubMed 
38191183

Print ISSN 
2059-8688
Online ISSN 
2059-8696
History 
  • Received May 25, 2023
  • Accepted November 28, 2023
  • Published online November 5, 2024.

Article Versions

  • Previous version (January 8, 2024 - 08:46).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

Author Information

  1. Lin Qi1,
  2. Cheng Wang1,
  3. Lidong Deng1,
  4. Jia-Ji Pan2,
  5. Qian Suo1,
  6. Shengju Wu1,
  7. Lin Cai3,
  8. Xudong Shi4,
  9. Junfeng Sun1,
  10. Yongting Wang1,
  11. Yaohui Tang1,
  12. Weibao Qiu4,
  13. Guo-Yuan Yang5,6,
  14. Jixian Wang6,
  15. Zhijun Zhang1
  1. 1 Shanghai Jiao Tong Affiliated Sixth People's Hospital, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, Shanghai, China
  2. 2 Department of Neurosurgery, Huashan Hospital, Shanghai Medical Collage, Fudan University, Shanghai, China
  3. 3 Department of Neurosurgery, Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University, Shanghai, China
  4. 4 Paul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Beijing, China
  5. 5 Neuroscience and Neuroengineering Center, Shanghai Jiao Tong University School of Biomedical Engineering, Shanghai, China
  6. 6 Shanghai Jiao Tong University Medical School Affiliated Ruijin Hospital, Shanghai, China
  1. Correspondence to Professor Zhijun Zhang; zhangzj{at}sjtu.edu.cn; Dr Jixian Wang; wangjixian6{at}163.com
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Vol 9 Issue 5 Table of Contents
Stroke and Vascular Neurology: 9 (5)
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Low-intensity focused ultrasound stimulation promotes stroke recovery via astrocytic HMGB1 and CAMK2N1 in mice
Lin Qi, Cheng Wang, Lidong Deng, Jia-Ji Pan, Qian Suo, Shengju Wu, Lin Cai, Xudong Shi, Junfeng Sun, Yongting Wang, Yaohui Tang, Weibao Qiu, Guo-Yuan Yang, Jixian Wang, Zhijun Zhang
Stroke and Vascular Neurology Oct 2024, 9 (5) 505-518; DOI: 10.1136/svn-2023-002614

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Low-intensity focused ultrasound stimulation promotes stroke recovery via astrocytic HMGB1 and CAMK2N1 in mice
Lin Qi, Cheng Wang, Lidong Deng, Jia-Ji Pan, Qian Suo, Shengju Wu, Lin Cai, Xudong Shi, Junfeng Sun, Yongting Wang, Yaohui Tang, Weibao Qiu, Guo-Yuan Yang, Jixian Wang, Zhijun Zhang
Stroke and Vascular Neurology Oct 2024, 9 (5) 505-518; DOI: 10.1136/svn-2023-002614
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Low-intensity focused ultrasound stimulation promotes stroke recovery via astrocytic HMGB1 and CAMK2N1 in mice
Lin Qi, Cheng Wang, Lidong Deng, Jia-Ji Pan, Qian Suo, Shengju Wu, Lin Cai, Xudong Shi, Junfeng Sun, Yongting Wang, Yaohui Tang, Weibao Qiu, Guo-Yuan Yang, Jixian Wang, Zhijun Zhang
Stroke and Vascular Neurology Oct 2024, 9 (5) 505-518; DOI: 10.1136/svn-2023-002614
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