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Open Access

Associations of polygenic risk scores with risks of stroke and its subtypes in Chinese

Songchun Yang, Zhijia Sun, Dong Sun, Canqing Yu, Yu Guo, Dianjianyi Sun, Yuanjie Pang, Pei Pei, Ling Yang, Iona Y Millwood, Robin G Walters, Yiping Chen, Huaidong Du, Yan Lu, Sushila Burgess, Daniel Avery, Robert Clarke, Junshi Chen, Zhengming Chen, Liming Li, Jun Lv
DOI: 10.1136/svn-2023-002428 Published 27 August 2024
Songchun Yang
1 Department of Epidemiology & Biostatistics, School of Public Health, Peking University, Beijing, China
2 Department of Dermatology, Xiangya Hospital, Central South University, Changsha, Hunan, China
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Zhijia Sun
1 Department of Epidemiology & Biostatistics, School of Public Health, Peking University, Beijing, China
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Dong Sun
1 Department of Epidemiology & Biostatistics, School of Public Health, Peking University, Beijing, China
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Canqing Yu
1 Department of Epidemiology & Biostatistics, School of Public Health, Peking University, Beijing, China
3 Peking University Center for Public Health and Epidemic Preparedness & Response, Beijing, China
4 Key Laboratory of Epidemiology of Major Diseases (Peking University), Ministry of Education, Beijing, China
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Yu Guo
5 Fuwai Hospital Chinese Academy of Medical Sciences, Beijing, China
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Dianjianyi Sun
1 Department of Epidemiology & Biostatistics, School of Public Health, Peking University, Beijing, China
3 Peking University Center for Public Health and Epidemic Preparedness & Response, Beijing, China
4 Key Laboratory of Epidemiology of Major Diseases (Peking University), Ministry of Education, Beijing, China
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Yuanjie Pang
1 Department of Epidemiology & Biostatistics, School of Public Health, Peking University, Beijing, China
4 Key Laboratory of Epidemiology of Major Diseases (Peking University), Ministry of Education, Beijing, China
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Pei Pei
3 Peking University Center for Public Health and Epidemic Preparedness & Response, Beijing, China
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Ling Yang
6 Medical Research Council Population Health Research Unit at the University of Oxford, Oxford, UK
7 Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK
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Iona Y Millwood
6 Medical Research Council Population Health Research Unit at the University of Oxford, Oxford, UK
7 Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK
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Robin G Walters
6 Medical Research Council Population Health Research Unit at the University of Oxford, Oxford, UK
7 Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK
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Yiping Chen
6 Medical Research Council Population Health Research Unit at the University of Oxford, Oxford, UK
7 Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK
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Huaidong Du
6 Medical Research Council Population Health Research Unit at the University of Oxford, Oxford, UK
7 Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK
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Yan Lu
8 NCDs Prevention and Control Department, Suzhou CDC, Suzhou, Jiangsu, China
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Sushila Burgess
7 Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK
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Daniel Avery
7 Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK
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Robert Clarke
7 Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK
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Junshi Chen
9 China National Center for Food Safety Risk Assessment, Beijing, China
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Zhengming Chen
7 Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK
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Liming Li
1 Department of Epidemiology & Biostatistics, School of Public Health, Peking University, Beijing, China
3 Peking University Center for Public Health and Epidemic Preparedness & Response, Beijing, China
4 Key Laboratory of Epidemiology of Major Diseases (Peking University), Ministry of Education, Beijing, China
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Jun Lv
1 Department of Epidemiology & Biostatistics, School of Public Health, Peking University, Beijing, China
3 Peking University Center for Public Health and Epidemic Preparedness & Response, Beijing, China
4 Key Laboratory of Epidemiology of Major Diseases (Peking University), Ministry of Education, Beijing, China
10 State Key Laboratory of Vascular Homeostasis and Remodeling, Peking University, Beijing, China
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Article Information

vol. 9 no. 4 399-406
DOI 
https://doi.org/10.1136/svn-2023-002428
PubMed 
37640499

Print ISSN 
2059-8688
Online ISSN 
2059-8696
History 
  • Received February 28, 2023
  • Accepted August 11, 2023
  • Published online August 27, 2024.

Article Versions

  • Previous version (August 28, 2023 - 08:07).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

Author Information

  1. Songchun Yang1,2,
  2. Zhijia Sun1,
  3. Dong Sun1,
  4. Canqing Yu1,3,4,
  5. Yu Guo5,
  6. Dianjianyi Sun1,3,4,
  7. Yuanjie Pang1,4,
  8. Pei Pei3,
  9. Ling Yang6,7,
  10. Iona Y Millwood6,7,
  11. Robin G Walters6,7,
  12. Yiping Chen6,7,
  13. Huaidong Du6,7,
  14. Yan Lu8,
  15. Sushila Burgess7,
  16. Daniel Avery7,
  17. Robert Clarke7,
  18. Junshi Chen9,
  19. Zhengming Chen7,
  20. Liming Li1,3,4,
  21. Jun Lv1,3,4,10
  22. On behalf of the China Kadoorie Biobank Collaborative Group
    1. 1 Department of Epidemiology & Biostatistics, School of Public Health, Peking University, Beijing, China
    2. 2 Department of Dermatology, Xiangya Hospital, Central South University, Changsha, Hunan, China
    3. 3 Peking University Center for Public Health and Epidemic Preparedness & Response, Beijing, China
    4. 4 Key Laboratory of Epidemiology of Major Diseases (Peking University), Ministry of Education, Beijing, China
    5. 5 Fuwai Hospital Chinese Academy of Medical Sciences, Beijing, China
    6. 6 Medical Research Council Population Health Research Unit at the University of Oxford, Oxford, UK
    7. 7 Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK
    8. 8 NCDs Prevention and Control Department, Suzhou CDC, Suzhou, Jiangsu, China
    9. 9 China National Center for Food Safety Risk Assessment, Beijing, China
    10. 10 State Key Laboratory of Vascular Homeostasis and Remodeling, Peking University, Beijing, China
    1. Correspondence to Dr Jun Lv; lvjun{at}bjmu.edu.cn
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    Associations of polygenic risk scores with risks of stroke and its subtypes in Chinese
    Songchun Yang, Zhijia Sun, Dong Sun, Canqing Yu, Yu Guo, Dianjianyi Sun, Yuanjie Pang, Pei Pei, Ling Yang, Iona Y Millwood, Robin G Walters, Yiping Chen, Huaidong Du, Yan Lu, Sushila Burgess, Daniel Avery, Robert Clarke, Junshi Chen, Zhengming Chen, Liming Li, Jun Lv
    Stroke and Vascular Neurology Aug 2024, 9 (4) 399-406; DOI: 10.1136/svn-2023-002428

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    Associations of polygenic risk scores with risks of stroke and its subtypes in Chinese
    Songchun Yang, Zhijia Sun, Dong Sun, Canqing Yu, Yu Guo, Dianjianyi Sun, Yuanjie Pang, Pei Pei, Ling Yang, Iona Y Millwood, Robin G Walters, Yiping Chen, Huaidong Du, Yan Lu, Sushila Burgess, Daniel Avery, Robert Clarke, Junshi Chen, Zhengming Chen, Liming Li, Jun Lv
    Stroke and Vascular Neurology Aug 2024, 9 (4) 399-406; DOI: 10.1136/svn-2023-002428
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    Associations of polygenic risk scores with risks of stroke and its subtypes in Chinese
    Songchun Yang, Zhijia Sun, Dong Sun, Canqing Yu, Yu Guo, Dianjianyi Sun, Yuanjie Pang, Pei Pei, Ling Yang, Iona Y Millwood, Robin G Walters, Yiping Chen, Huaidong Du, Yan Lu, Sushila Burgess, Daniel Avery, Robert Clarke, Junshi Chen, Zhengming Chen, Liming Li, Jun Lv
    Stroke and Vascular Neurology Aug 2024, 9 (4) 399-406; DOI: 10.1136/svn-2023-002428
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