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Cerebral venous sinus thrombosis: changing trends in the incidence, age and gender (findings from the CMC Vellore CVT registry)

Angel Miraclin T, John Davis Prasad, George Abraham Ninan, Mahasampath Gowri, Deepti Bal, Atif Iqbal Ahmed Shaikh, Rohit N Benjamin, Appaswamy Thirumal Prabhakar, Ajith Sivadasan, Vivek Mathew, Sanjith Aaron
DOI: 10.1136/svn-2023-002351 Published 21 June 2024
Angel Miraclin T
1 Department of Neurological Sciences, Christian Medical College, Vellore, Tamil Nadu, India
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John Davis Prasad
1 Department of Neurological Sciences, Christian Medical College, Vellore, Tamil Nadu, India
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George Abraham Ninan
1 Department of Neurological Sciences, Christian Medical College, Vellore, Tamil Nadu, India
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Mahasampath Gowri
2 Department of Biostatistics, Christian Medical College, Vellore, Tamil Nadu, India
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Deepti Bal
1 Department of Neurological Sciences, Christian Medical College, Vellore, Tamil Nadu, India
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Atif Iqbal Ahmed Shaikh
1 Department of Neurological Sciences, Christian Medical College, Vellore, Tamil Nadu, India
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Rohit N Benjamin
1 Department of Neurological Sciences, Christian Medical College, Vellore, Tamil Nadu, India
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Appaswamy Thirumal Prabhakar
1 Department of Neurological Sciences, Christian Medical College, Vellore, Tamil Nadu, India
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Ajith Sivadasan
1 Department of Neurological Sciences, Christian Medical College, Vellore, Tamil Nadu, India
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Vivek Mathew
1 Department of Neurological Sciences, Christian Medical College, Vellore, Tamil Nadu, India
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Sanjith Aaron
1 Department of Neurological Sciences, Christian Medical College, Vellore, Tamil Nadu, India
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    Figure 1

    Distribution of patients across India.

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    Figure 2

    Change in incidence of CVT before and after 2010 (p<0.001). CVT, cerebral venous sinus thrombosis.

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    Figure 3

    (A) Gender trends in CVT from 1995 to 2021, (B) fitted linear regression with quadratic terms showing an increase in males after 2012 (p - 0.001).

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    Figure 4

    (A) Trends comparing the distribution of CVT in females, with and without postpartum, (B) fitted linear regression in quadratic terms showing a significant decline in postpartum CVT (p - 0.001). CVT, cerebral venous sinus thrombosis.

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    Figure 5

    Age trends in CVT from 1995 to 2021. CVT, cerebral venous sinus thrombosis.

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    Figure 6

    World data on the share of the population that is female (adapted from OurWorldInData.Org). Source: World Bank based on data from the UN Population Division. Note: Population is based on the de facto definition of population, which counts all residents regardless of legal status or citizenship.

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    Figure 7

    Sex ratio by age in India (adapted from OurWorldInData.Org). Source: OWID based on UN (2002).

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Vol 9 Issue 3 Table of Contents
Stroke and Vascular Neurology: 9 (3)
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Cerebral venous sinus thrombosis: changing trends in the incidence, age and gender (findings from the CMC Vellore CVT registry)
Angel Miraclin T, John Davis Prasad, George Abraham Ninan, Mahasampath Gowri, Deepti Bal, Atif Iqbal Ahmed Shaikh, Rohit N Benjamin, Appaswamy Thirumal Prabhakar, Ajith Sivadasan, Vivek Mathew, Sanjith Aaron
Stroke and Vascular Neurology Jun 2024, 9 (3) 252-257; DOI: 10.1136/svn-2023-002351

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Cerebral venous sinus thrombosis: changing trends in the incidence, age and gender (findings from the CMC Vellore CVT registry)
Angel Miraclin T, John Davis Prasad, George Abraham Ninan, Mahasampath Gowri, Deepti Bal, Atif Iqbal Ahmed Shaikh, Rohit N Benjamin, Appaswamy Thirumal Prabhakar, Ajith Sivadasan, Vivek Mathew, Sanjith Aaron
Stroke and Vascular Neurology Jun 2024, 9 (3) 252-257; DOI: 10.1136/svn-2023-002351
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Cerebral venous sinus thrombosis: changing trends in the incidence, age and gender (findings from the CMC Vellore CVT registry)
Angel Miraclin T, John Davis Prasad, George Abraham Ninan, Mahasampath Gowri, Deepti Bal, Atif Iqbal Ahmed Shaikh, Rohit N Benjamin, Appaswamy Thirumal Prabhakar, Ajith Sivadasan, Vivek Mathew, Sanjith Aaron
Stroke and Vascular Neurology Jun 2024, 9 (3) 252-257; DOI: 10.1136/svn-2023-002351
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