Open Access
Prehospital transdermal glyceryl trinitrate for ultra-acute ischaemic stroke: data from the RIGHT-2 randomised sham-controlled ambulance trial
Jason Philip Appleton, Lisa J Woodhouse, Craig S Anderson, Sandeep Ankolekar, Lesley Cala, Mark Dixon, Timothy J England, Kailash Krishnan, Grant Mair, Keith W Muir, John Potter, Christopher I Price, Marc Randall, Thompson G Robinson, Christine Roffe, Else C Sandset, Jeffrey L Saver, Angela Shone, Aloysius Niroshan Siriwardena, Joanna M Wardlaw, Nikola Sprigg, Philip M Bath
DOI: 10.1136/svn-2022-001634 Published 27 February 2024
Jason Philip Appleton
1
Stroke, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
2
Institute of Applied Health Research, University of Birmingham College of Medical and Dental Sciences, Birmingham, UK
Lisa J Woodhouse
3
Stroke Trials Unit, Mental Health and Clinical Neurosciences, University of Nottingham, Nottingham, UK
Craig S Anderson
4
Faculty of Medicine, The George Institute for Global Health, Sydney, New South Wales, Australia
5
The George Institute China at Peking University Health Science Center, Beijing, China
6
Neurology, Royal Prince Alfred Hospital, Sydney Health Partners, Sydney, New South Wales, Australia
Sandeep Ankolekar
7
Department of Neurology, King's College Hospital NHS Foundation Trust, London, UK
Lesley Cala
8
Faculty of Health and Medical Sciences, University of Western Australia, Crawley, Western Australia, Australia
Mark Dixon
3
Stroke Trials Unit, Mental Health and Clinical Neurosciences, University of Nottingham, Nottingham, UK
9
East Midlands Ambulance Service NHS Trust, Nottingham, UK
Timothy J England
3
Stroke Trials Unit, Mental Health and Clinical Neurosciences, University of Nottingham, Nottingham, UK
Kailash Krishnan
10
Stroke, Queen's Medical Centre, Nottingham University Hospitals NHS Trust, Nottingham, UK
Grant Mair
11
Centre for Clinical Brain Sciences, Dementia Research Institute, Univeristy of Edinburgh, Edinburgh, UK
Keith W Muir
12
Institute of Neurology and Psychology, University of Glasgow, Glasgow, UK
John Potter
13
Bob Champion Research and Education Building, University of East Anglia, Norwich, UK
Christopher I Price
14
Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, UK
Marc Randall
15
Department of Neurology, Leeds Teaching Hospitals NHS Trust, Leeds, UK
Thompson G Robinson
16
Department of Cardiovascular Sciences and NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK
Christine Roffe
17
Stroke Research in Stoke, Institute for Science and Technology in Medicine, Keele University, Stoke-on-Trent, UK
Else C Sandset
18
Department of Neurology, Oslo University Hospital, Oslo, Norway
19
Research and Development, Norwegian Air Ambulance Foundation, Oslo, Norway
Jeffrey L Saver
20
Department of Neurology and Comprehensive Stroke Center, David Geffen School of Medicine, UCLA, Los Angeles, California, USA
Angela Shone
21
Research and Graduate Services, University of Nottingham, Nottingham, UK
Aloysius Niroshan Siriwardena
9
East Midlands Ambulance Service NHS Trust, Nottingham, UK
22
Community and Health Research Unit, University of Lincoln, Lincoln, UK
Joanna M Wardlaw
11
Centre for Clinical Brain Sciences, Dementia Research Institute, Univeristy of Edinburgh, Edinburgh, UK
Nikola Sprigg
3
Stroke Trials Unit, Mental Health and Clinical Neurosciences, University of Nottingham, Nottingham, UK
10
Stroke, Queen's Medical Centre, Nottingham University Hospitals NHS Trust, Nottingham, UK
Philip M Bath
3
Stroke Trials Unit, Mental Health and Clinical Neurosciences, University of Nottingham, Nottingham, UK
10
Stroke, Queen's Medical Centre, Nottingham University Hospitals NHS Trust, Nottingham, UK

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Prehospital transdermal glyceryl trinitrate for ultra-acute ischaemic stroke: data from the RIGHT-2 randomised sham-controlled ambulance trial
Jason Philip Appleton, Lisa J Woodhouse, Craig S Anderson, Sandeep Ankolekar, Lesley Cala, Mark Dixon, Timothy J England, Kailash Krishnan, Grant Mair, Keith W Muir, John Potter, Christopher I Price, Marc Randall, Thompson G Robinson, Christine Roffe, Else C Sandset, Jeffrey L Saver, Angela Shone, Aloysius Niroshan Siriwardena, Joanna M Wardlaw, Nikola Sprigg, Philip M Bath
Stroke and Vascular Neurology Feb 2024, 9 (1) 38-49; DOI: 10.1136/svn-2022-001634

Prehospital transdermal glyceryl trinitrate for ultra-acute ischaemic stroke: data from the RIGHT-2 randomised sham-controlled ambulance trial
Jason Philip Appleton, Lisa J Woodhouse, Craig S Anderson, Sandeep Ankolekar, Lesley Cala, Mark Dixon, Timothy J England, Kailash Krishnan, Grant Mair, Keith W Muir, John Potter, Christopher I Price, Marc Randall, Thompson G Robinson, Christine Roffe, Else C Sandset, Jeffrey L Saver, Angela Shone, Aloysius Niroshan Siriwardena, Joanna M Wardlaw, Nikola Sprigg, Philip M Bath
Stroke and Vascular Neurology Feb 2024, 9 (1) 38-49; DOI: 10.1136/svn-2022-001634
Prehospital transdermal glyceryl trinitrate for ultra-acute ischaemic stroke: data from the RIGHT-2 randomised sham-controlled ambulance trial
Jason Philip Appleton, Lisa J Woodhouse, Craig S Anderson, Sandeep Ankolekar, Lesley Cala, Mark Dixon, Timothy J England, Kailash Krishnan, Grant Mair, Keith W Muir, John Potter, Christopher I Price, Marc Randall, Thompson G Robinson, Christine Roffe, Else C Sandset, Jeffrey L Saver, Angela Shone, Aloysius Niroshan Siriwardena, Joanna M Wardlaw, Nikola Sprigg, Philip M Bath
Stroke and Vascular Neurology Feb 2024, 9 (1) 38-49; DOI: 10.1136/svn-2022-001634