Open Access
Endovascular thrombectomy with or without intravenous alteplase for acute ischemic stroke due to large vessel occlusion: a systematic review and meta-analysis of randomized trials
Xin Wang, Zhikang Ye, Jason W Busse, Michael D Hill, Eric E Smith, Gordon H Guyatt, Kameshwar Prasad, M Patrice Lindsay, Hui Yang, Yi Zhang, Ying Liu, Borui Tang, Xinrui Wang, Yushu Wang, Rachel J Couban, Zhuoling An
DOI: 10.1136/svn-2022-001547 Published 20 December 2022
Xin Wang
1
Department of Pharmacy, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
Zhikang Ye
1
Department of Pharmacy, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
2
Michael G DeGroote National Pain Centre, McMaster University, Hamilton, Ontario, Canada
Jason W Busse
2
Michael G DeGroote National Pain Centre, McMaster University, Hamilton, Ontario, Canada
3
Department of Health Research Methods Evidence and Impact, McMaster University, Hamilton, Ontario, Canada
4
Department of Anesthesia, McMaster University, Hamilton, Ontario, Canada
Michael D Hill
5
Department of Clinical Neurosciences and Hotchkiss Brain Institute, Departments of Medicine, Community Health Sciences and Radiology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada
Eric E Smith
6
Department of Clinical Neurosciences and Calgary Stroke Program, University of Calgary, Calgary, Alberta, Canada
Gordon H Guyatt
3
Department of Health Research Methods Evidence and Impact, McMaster University, Hamilton, Ontario, Canada
Kameshwar Prasad
7
Professor of neurology and Director, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India
M Patrice Lindsay
8
Heart and Stroke Foundation of Canada, Toronto, Ontario, Canada
Hui Yang
1
Department of Pharmacy, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
Yi Zhang
1
Department of Pharmacy, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
9
Department of Pharmacy, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, China
Ying Liu
1
Department of Pharmacy, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
Borui Tang
1
Department of Pharmacy, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
Xinrui Wang
1
Department of Pharmacy, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
9
Department of Pharmacy, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, China
Yushu Wang
1
Department of Pharmacy, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
9
Department of Pharmacy, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, China
Rachel J Couban
10
DeGroote Institute for Pain Research and Care, McMaster University, Hamilton, Ontario, Canada
Zhuoling An
1
Department of Pharmacy, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China

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Endovascular thrombectomy with or without intravenous alteplase for acute ischemic stroke due to large vessel occlusion: a systematic review and meta-analysis of randomized trials
Xin Wang, Zhikang Ye, Jason W Busse, Michael D Hill, Eric E Smith, Gordon H Guyatt, Kameshwar Prasad, M Patrice Lindsay, Hui Yang, Yi Zhang, Ying Liu, Borui Tang, Xinrui Wang, Yushu Wang, Rachel J Couban, Zhuoling An
Stroke and Vascular Neurology Dec 2022, 7 (6) 510-517; DOI: 10.1136/svn-2022-001547

Endovascular thrombectomy with or without intravenous alteplase for acute ischemic stroke due to large vessel occlusion: a systematic review and meta-analysis of randomized trials
Xin Wang, Zhikang Ye, Jason W Busse, Michael D Hill, Eric E Smith, Gordon H Guyatt, Kameshwar Prasad, M Patrice Lindsay, Hui Yang, Yi Zhang, Ying Liu, Borui Tang, Xinrui Wang, Yushu Wang, Rachel J Couban, Zhuoling An
Stroke and Vascular Neurology Dec 2022, 7 (6) 510-517; DOI: 10.1136/svn-2022-001547
Endovascular thrombectomy with or without intravenous alteplase for acute ischemic stroke due to large vessel occlusion: a systematic review and meta-analysis of randomized trials
Xin Wang, Zhikang Ye, Jason W Busse, Michael D Hill, Eric E Smith, Gordon H Guyatt, Kameshwar Prasad, M Patrice Lindsay, Hui Yang, Yi Zhang, Ying Liu, Borui Tang, Xinrui Wang, Yushu Wang, Rachel J Couban, Zhuoling An
Stroke and Vascular Neurology Dec 2022, 7 (6) 510-517; DOI: 10.1136/svn-2022-001547