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Endovascular thrombectomy with or without intravenous alteplase for acute ischemic stroke due to large vessel occlusion: a systematic review and meta-analysis of randomized trials

Xin Wang, Zhikang Ye, Jason W Busse, Michael D Hill, Eric E Smith, Gordon H Guyatt, Kameshwar Prasad, M Patrice Lindsay, Hui Yang, Yi Zhang, Ying Liu, Borui Tang, Xinrui Wang, Yushu Wang, Rachel J Couban, Zhuoling An
DOI: 10.1136/svn-2022-001547 Published 20 December 2022
Xin Wang
1 Department of Pharmacy, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
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Zhikang Ye
1 Department of Pharmacy, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
2 Michael G DeGroote National Pain Centre, McMaster University, Hamilton, Ontario, Canada
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Jason W Busse
2 Michael G DeGroote National Pain Centre, McMaster University, Hamilton, Ontario, Canada
3 Department of Health Research Methods Evidence and Impact, McMaster University, Hamilton, Ontario, Canada
4 Department of Anesthesia, McMaster University, Hamilton, Ontario, Canada
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Michael D Hill
5 Department of Clinical Neurosciences and Hotchkiss Brain Institute, Departments of Medicine, Community Health Sciences and Radiology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada
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Eric E Smith
6 Department of Clinical Neurosciences and Calgary Stroke Program, University of Calgary, Calgary, Alberta, Canada
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Gordon H Guyatt
3 Department of Health Research Methods Evidence and Impact, McMaster University, Hamilton, Ontario, Canada
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Kameshwar Prasad
7 Professor of neurology and Director, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India
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M Patrice Lindsay
8 Heart and Stroke Foundation of Canada, Toronto, Ontario, Canada
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Hui Yang
1 Department of Pharmacy, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
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Yi Zhang
1 Department of Pharmacy, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
9 Department of Pharmacy, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, China
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Ying Liu
1 Department of Pharmacy, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
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Borui Tang
1 Department of Pharmacy, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
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Xinrui Wang
1 Department of Pharmacy, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
9 Department of Pharmacy, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, China
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Yushu Wang
1 Department of Pharmacy, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
9 Department of Pharmacy, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, China
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Rachel J Couban
10 DeGroote Institute for Pain Research and Care, McMaster University, Hamilton, Ontario, Canada
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Zhuoling An
1 Department of Pharmacy, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
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Article Information

vol. 7 no. 6 510-517
DOI 
https://doi.org/10.1136/svn-2022-001547
PubMed 
35725244

Print ISSN 
2059-8688
Online ISSN 
2059-8696
History 
  • Received February 16, 2022
  • Accepted May 23, 2022
  • Published online December 20, 2022.

Article Versions

  • Previous version (June 20, 2022 - 07:00).
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Copyright & Usage 
© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

Author Information

  1. Xin Wang1,
  2. Zhikang Ye1,2,
  3. Jason W Busse2,3,4,
  4. Michael D Hill5,
  5. Eric E Smith6,
  6. Gordon H Guyatt3,
  7. Kameshwar Prasad7,
  8. M Patrice Lindsay8,
  9. Hui Yang1,
  10. Yi Zhang1,9,
  11. Ying Liu1,
  12. Borui Tang1,
  13. Xinrui Wang1,9,
  14. Yushu Wang1,9,
  15. Rachel J Couban10,
  16. Zhuoling An1
  1. 1 Department of Pharmacy, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
  2. 2 Michael G DeGroote National Pain Centre, McMaster University, Hamilton, Ontario, Canada
  3. 3 Department of Health Research Methods Evidence and Impact, McMaster University, Hamilton, Ontario, Canada
  4. 4 Department of Anesthesia, McMaster University, Hamilton, Ontario, Canada
  5. 5 Department of Clinical Neurosciences and Hotchkiss Brain Institute, Departments of Medicine, Community Health Sciences and Radiology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada
  6. 6 Department of Clinical Neurosciences and Calgary Stroke Program, University of Calgary, Calgary, Alberta, Canada
  7. 7 Professor of neurology and Director, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India
  8. 8 Heart and Stroke Foundation of Canada, Toronto, Ontario, Canada
  9. 9 Department of Pharmacy, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, China
  10. 10 DeGroote Institute for Pain Research and Care, McMaster University, Hamilton, Ontario, Canada
  1. Correspondence to Zhuoling An; anzhuoling{at}163.com
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Endovascular thrombectomy with or without intravenous alteplase for acute ischemic stroke due to large vessel occlusion: a systematic review and meta-analysis of randomized trials
Xin Wang, Zhikang Ye, Jason W Busse, Michael D Hill, Eric E Smith, Gordon H Guyatt, Kameshwar Prasad, M Patrice Lindsay, Hui Yang, Yi Zhang, Ying Liu, Borui Tang, Xinrui Wang, Yushu Wang, Rachel J Couban, Zhuoling An
Stroke and Vascular Neurology Dec 2022, 7 (6) 510-517; DOI: 10.1136/svn-2022-001547

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Endovascular thrombectomy with or without intravenous alteplase for acute ischemic stroke due to large vessel occlusion: a systematic review and meta-analysis of randomized trials
Xin Wang, Zhikang Ye, Jason W Busse, Michael D Hill, Eric E Smith, Gordon H Guyatt, Kameshwar Prasad, M Patrice Lindsay, Hui Yang, Yi Zhang, Ying Liu, Borui Tang, Xinrui Wang, Yushu Wang, Rachel J Couban, Zhuoling An
Stroke and Vascular Neurology Dec 2022, 7 (6) 510-517; DOI: 10.1136/svn-2022-001547
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Endovascular thrombectomy with or without intravenous alteplase for acute ischemic stroke due to large vessel occlusion: a systematic review and meta-analysis of randomized trials
Xin Wang, Zhikang Ye, Jason W Busse, Michael D Hill, Eric E Smith, Gordon H Guyatt, Kameshwar Prasad, M Patrice Lindsay, Hui Yang, Yi Zhang, Ying Liu, Borui Tang, Xinrui Wang, Yushu Wang, Rachel J Couban, Zhuoling An
Stroke and Vascular Neurology Dec 2022, 7 (6) 510-517; DOI: 10.1136/svn-2022-001547
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