Article Figures & Data
- Table 1
Comparison of the PED alone and PED combined with coiling groups before propensity score matching in the 967 aneurysms with angiographic follow-up
Variable PED alone PED combining coils P value No. of aneurysms (%) 496 471 Age (years) 14–82 3–78 Mean (SD) 53.06 (±11.11) 54.30 (±11.36) 0.084 Female 330 (66.5) 368 (78.1) <0.001 Comorbidities Hypertension 150 (30.2) 168 (35.7) 0.073 Diabetes 19 (3.8) 27 (5.7) 0.165 Hyperlipidaemia 21 (4.2) 14 (3.0) 0.305 Coronary heart disease 28 (5.6） 22 (4.7） 0.494 Alcohol abuse 68 (13.7） 46 (9.8） 0.057 Smoking 140 (28.2） 102 (21.7） 0.018 Aneurysm presentation 0.006 Incidental 262 (52.8) 202 (42.9) 0.002 Symptomatic 217 (43.8) 254 (53.9) 0.002 Ruptured (history of SAH) 17 (3.4) 15 (3.2) 0.833 Pretreatment mRS 0.807 ≤2 455 (91.7) 430 (91.3) >2 41 (8.3) 41 (8.7) Multiple aneurysms 159 (32.1) 133 (28.2) 0.196 Ruptured aneurysms 17 (3.4) 15 (3.2) 0.833 Morphology <0.001 Saccular 379 (76.4) 430 (91.8) <0.001 Fusiform 58 (11.7) 24 (4.8) 0.001 Dissecting 47 (9.5) 11 (2.2) <0.001 Blister 12 (2.4) 6 (1.2) 0.188 Maximal diameter in mm (mean） 9.99 (±7.57) 15.13 (±8.08) <0.001 ≤7 mm 230 (46.4) 86 (18.3) <0.001 7–15 mm 168 (33.9) 197 (41.8) 0.011 >15 mm 98 (19.7) 188 (39.9) <0.001 Location <0.001 Carotid artery 376 (75.8) 419 (89.6) <0.001 Distal circle of Willis 25 (5.1) 14 (3.0) 0.102 Vertebral artery 82 (16.5) 24 (5.0) <0.001 Basilar artery and other posterior circulation 13 (2.6) 14 (3.0) 0.740 PED model 0.116 PED Classic 213 (42.9%） 226 (48.0%） PED Flex 283 (57.1) 245 (52.0) Time to last follow-up imaging (mean) 9.05 (±6.53) 9.01 (±7.59) 0.574 Complete occlusion at last follow-up 382 (77.0) 407 (86.4) <0.001 mRS score at last follow-up 0.554 ≤2 458 (92.3) 430 (91.3) >2 38 (7.7) 41 (8.7) Complications Ischaemic complications 27 (5.4) 58 (12.1) <0.001 Haemorrhagic complications 22 (4.5) 24 (5.1) 0.681 DAR 12 (2.4) 11 (2.3) 0.932 DIPH 10 (2.0) 13 (2.8) 0.448 Compression symptoms 20 (4.0) 31 (6.6) 0.076 Mortality 9 (1.8) 9 (1.9) 0.912 Bold values: p value <0.05.
n (%); p value: χ2 test.
Median (IQR); p value: t-test.
DAR, delayed aneurysm rupture; DIPH, distal intraparenchymal haemorrhage; mRS, modified Rankin scale; PED, Pipeline embolisation device; SAH, subarachnoid haemorrhage.
- Table 2
The relation between size and complete occlusion (aneurysms number=967)
Aneurysm size Total PED alone PED coils P value ≤7 mm 258/316 (81.6) 182/230 (79.1) 76/86 (88.4) 0.059 ≤15 mm to >7 mm 300/365 (82.2) 125/168 (74.7) 175/197 (88.8) <0.0001 >15 mm 231/286 (83.7) 75/98 (76.5) 156/188 (83.0) 0.189 >15 mm (saccular) 162/196 (82.7) 43/59 (72.9) 119/137 (86.9) 0.018 >15 mm (non-saccular) 69/90 (76.7) 32/39 (82.1) 37/51 (72.5) 0.291 Bold values: p value <0.05.
n (%); p value: χ2 test.
A total of 858 patients with 967 aneurysms underwent angiography follow-up.
PED, Pipeline embolisation device.
- Table 3
The relation between size and total complication (ischaemic and haemorrhage complication) (aneurysms number=1322)
Aneurysm size Total PED PED coils P value ≤7 mm 48/436 (11.0) 27/327 (8.3) 21/109 (19.3) 0.0001 ≤15 mm to >7 mm 49/470 (10.4) 19/227 (8.4) 30/243 (12.3) 0.174 >15 mm 55/416 (13.2) 16/129 (12.4) 39/287 (13.6) 0.741 >15 mm (saccular) 40/293 (16.7) 12/71 (16.9) 28/222 (12.6) 0.360 >15 mm (non-saccular) 15/122 (12.3) 4/58 (6.9) 11/64 (17.2) 0.084 Bold values: p value <0.05.
n (%); p value: χ2 test.
PED, Pipeline embolisation device.
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