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Non-compliant and compliant balloons for endovascular rescue therapy of cerebral vasospasm after spontaneous subarachnoid haemorrhage: experiences of a single-centre institution with radiological follow-up of the treated vessel segments

Alexander Neumann, Jan Küchler, Claudia Ditz, Kara Krajewski, Jan Leppert, Peter Schramm, Hannes Schacht
DOI: 10.1136/svn-2020-000410 Published 25 March 2021
Alexander Neumann
1 Neuroradiology, University Medical Center Schleswig Holstein Lubeck Campus, Lubeck, Germany
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Jan Küchler
2 Neurosurgery, University Medical Center Schleswig Holstein Lubeck Campus, Lubeck, Germany
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Claudia Ditz
2 Neurosurgery, University Medical Center Schleswig Holstein Lubeck Campus, Lubeck, Germany
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Kara Krajewski
2 Neurosurgery, University Medical Center Schleswig Holstein Lubeck Campus, Lubeck, Germany
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Jan Leppert
2 Neurosurgery, University Medical Center Schleswig Holstein Lubeck Campus, Lubeck, Germany
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Peter Schramm
1 Neuroradiology, University Medical Center Schleswig Holstein Lubeck Campus, Lubeck, Germany
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Hannes Schacht
1 Neuroradiology, University Medical Center Schleswig Holstein Lubeck Campus, Lubeck, Germany
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  • Figure 1
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    Figure 1

    Illustration of (A) cerebral vasospasm and its endovascular treatment with angioplasty using a (B) non-compliant or a (C) compliant (with hypothetical ‘dog-bone’ phenomenon) balloon.

  • Figure 2
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    Figure 2

    Angiogram before (A) and after (B) TBA with a CB in connection with severe CVS in the distal ICA as well as within the proximal segments of the MCA and ACA. Mild arterial narrowing in the catheter angiography and TOF MRA, 6 months later (C). ACA, anterior cerebral artery; CB, compliant balloons; CVS, cerebral vasospasm; ICA, internal carotid artery; MCA, middle cerebral artery; TBA, transluminal balloon angioplasty; TOF MRA, time-of-flight magnetic resonance angiography.

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    Figure 3

    Angiogram before (A) and after (B) TBA with a CB in connection with severe CVS in the distal ICA as well as the proximal segments of the MCA and ACA. No arterial narrowing is visible in the TOF MRA 11 months later (C). ACA, anterior cerebral artery; CB, compliant balloon; CVS, cerebral vasospasm; ICA, internal carotid artery; MCA, middle cerebral artery; TBA; transluminal balloon angioplasty; TOF MRA, time-of-flight magnetic resonance angiography.

Tables

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  • Table 1

    Patient data, clinical characteristics, endovascular rescue therapy and outcome

    Patient numberClinical characteristicsEndovascular rescue therapyOutcome
    AgeGenderWFNS gradeFisher scaleAneurysm localisationAneurysm obliterationLocalisation of TBAIntra-arterial nimodipineBalloon type (NCB, CB)ComplicationsCVS-associated infarctionIn-hpospital mortalitymRS after 3 months
    151f23BACoilingMCA+NCB 2.0×9 mm Gateway (Boston Scientific)–––4
    233f44ICACoilingICA+ACA+MCA+CB 4.0×10 mm HyperGlide (Medtronic)–––2
    335m24SCACoilingICA+NCB 2.5×20 mm Ryujin Plus (Terumo)–––3
    465f33MCACoilingMCA+CB 4.0×7 mm TransForm (Stryker)–+–4
    546m53MCACoiling/stent-assistedMCA+CB 4.0×7 mm TransForm (Stryker)–+–4
    639f13ACACoilingICA+ACA+MCA+VAS+CB 4.0×15 mm X-Pedion HyperGlide (Medtronic),
    NCB 2.5×9 mm Maverick (Boston Scientific)
    –––2
    733m13Angiogram-negative–ICA+MCA+CB 4.0×7 mm X-Pedion HyperForm (Medtronic)–––0
    830f12BACoiling/stent-assistedACA–CB 4.0×10 mm X-Pedion HyperGlide (Medtronic)–––2
    978f54PCOMCoiling/stent-assistedMCA–CB 4.0×7 mm TransForm (Stryker)–++6
    1038f13ICACoilingACA+MCA+CB 4.0×10 mm TransForm (Stryker)–––1
    1152f44ICACoiling/stent-assistedACA+MCA+CB 4.0×10 mm TransForm (Stryker)–––4
    1225f13MCAWEB-DeviceMCA+CB 4.0×10 mm TransForm (Stryker)–––1
    • ACA, anterior cerebral artery; BA, basilar artery; CB, compliant balloon; CVS, cerebral vasospasm; ICA, internal carotid artery; MCA, middle cerebral artery; mRS, modified Rankin scale; NCB, non-compliant balloon; PCOM, posterior communicating artery; SCA, superior cerebellar artery; TBA, transluminal balloon angioplasty; WFNS, World Federation of Neurosurgical Societies.

  • Table 2

    Data on endovascular rescue therapy and radiological follow-up

    Compliant
    balloon
    Non-compliant
    balloon
    P-value
    No. of treated vessel segments237
    Localisation0.194
     ICA3 (0.13)3 (0.43)
     ACA7 (0.30)0 (0.00)
     MCA11 (0.48)3 (0.43)
     VAS2 (0.09)1 (0.14)
    Median radiological follow-up (range)
    (in months)
    11 (5–26)10 (7–28)0.701
    Imaging modalities0.532
     Catheter angiography18 (0.78)5 (0.71)
     TOF MRA5 (0.22)2 (0.29)
    Arterial narrowing in radiological follow-up0.677
     Mild3 (0.13)1 (0.14)
     Moderate or severe0 (0.00)0 (0.00)
    • ACA, anterior cerebral artery; ICA, internal carotid artery; MCA, middle cerebral artery; TOF MRA, time-of-flight magnetic resonance angiography; VAS, vertebrobasilar arterial system.

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Non-compliant and compliant balloons for endovascular rescue therapy of cerebral vasospasm after spontaneous subarachnoid haemorrhage: experiences of a single-centre institution with radiological follow-up of the treated vessel segments
Alexander Neumann, Jan Küchler, Claudia Ditz, Kara Krajewski, Jan Leppert, Peter Schramm, Hannes Schacht
Stroke and Vascular Neurology Mar 2021, 6 (1) 16-24; DOI: 10.1136/svn-2020-000410

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Non-compliant and compliant balloons for endovascular rescue therapy of cerebral vasospasm after spontaneous subarachnoid haemorrhage: experiences of a single-centre institution with radiological follow-up of the treated vessel segments
Alexander Neumann, Jan Küchler, Claudia Ditz, Kara Krajewski, Jan Leppert, Peter Schramm, Hannes Schacht
Stroke and Vascular Neurology Mar 2021, 6 (1) 16-24; DOI: 10.1136/svn-2020-000410
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Non-compliant and compliant balloons for endovascular rescue therapy of cerebral vasospasm after spontaneous subarachnoid haemorrhage: experiences of a single-centre institution with radiological follow-up of the treated vessel segments
Alexander Neumann, Jan Küchler, Claudia Ditz, Kara Krajewski, Jan Leppert, Peter Schramm, Hannes Schacht
Stroke and Vascular Neurology Mar 2021, 6 (1) 16-24; DOI: 10.1136/svn-2020-000410
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