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Intra-arterial tenecteplase after successful endovascular therapy (ANGEL-TNK): protocol of a multicentre, open-label, blinded end-point, prospective, randomised trial

Xiaochuan Huo, Gang Luo, Dapeng Sun, Thanh Nguyen, Mohamad Abdalkader, Wenhuo Chen, Xiaoxi Yao, Guangxiong Yuan, Tingyu Yi, Hongxin Han, Yuesong Pan, Tudor G Jovin, David S Liebeskind, Liping Liu, Xingquan Zhao, Zeguang Ren, Yilong Wang, Yongjun Wang, Bernard Yan, Zhongrong Miao
DOI: 10.1136/svn-2024-003318 Published 21 November 2024
Xiaochuan Huo
1Cerebrovascular Disease Department, Neurological Disease Center, Beijing Anzhen Hospital, Capital Medical University, Beijing, China
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Gang Luo
2Interventional Neuroradiology, Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
3China National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
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Dapeng Sun
2Interventional Neuroradiology, Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
3China National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
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Thanh Nguyen
4Neurology, Radiology, Boston Medical Center, Boston, Massachusetts, USA
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Mohamad Abdalkader
4Neurology, Radiology, Boston Medical Center, Boston, Massachusetts, USA
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Wenhuo Chen
5Department of Neurology, Fujian Medical University Union Hospital, Fuzhou, Fujian, China
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Xiaoxi Yao
6Department of Neurology, Affiliated Chenzhou Hospital, Southern Medical University (The First People’s Hospital of Chenzhou), The First People's Hospital of Chenzhou, Chenzhou, China
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Guangxiong Yuan
7Department of Emergency, Xiangtan Central Hospital, Xiangtan, China
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Tingyu Yi
8Department of Neurology, Zhangzhou Municipal Hospital of Fujian Province and Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, China
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Hongxin Han
9Department of Neurology, Linyi People's Hospital, Linyi, Shandong, China
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Yuesong Pan
3China National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
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Tudor G Jovin
10Cooper Hospital University Medical Center, Camden, New Jersey, USA
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David S Liebeskind
11University of California Los Angeles, Los Angeles, California, USA
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Liping Liu
3China National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
12Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
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Xingquan Zhao
12Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
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Zeguang Ren
13Department of Neurosurgery, The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China
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Yilong Wang
3China National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
12Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
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Yongjun Wang
3China National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
12Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
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Bernard Yan
14Department of Neurology at Melbourne Brain Center, The University of Melbourne Medicine at Royal Melbourne Hospital, Parkville, Victoria, Australia
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Zhongrong Miao
2Interventional Neuroradiology, Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
3China National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
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Stroke and Vascular Neurology: 10 (1)
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Intra-arterial tenecteplase after successful endovascular therapy (ANGEL-TNK): protocol of a multicentre, open-label, blinded end-point, prospective, randomised trial
Xiaochuan Huo, Gang Luo, Dapeng Sun, Thanh Nguyen, Mohamad Abdalkader, Wenhuo Chen, Xiaoxi Yao, Guangxiong Yuan, Tingyu Yi, Hongxin Han, Yuesong Pan, Tudor G Jovin, David S Liebeskind, Liping Liu, Xingquan Zhao, Zeguang Ren, Yilong Wang, Yongjun Wang, Bernard Yan, Zhongrong Miao
Stroke and Vascular Neurology Oct 2024, svn-2024-003318; DOI: 10.1136/svn-2024-003318

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Intra-arterial tenecteplase after successful endovascular therapy (ANGEL-TNK): protocol of a multicentre, open-label, blinded end-point, prospective, randomised trial
Xiaochuan Huo, Gang Luo, Dapeng Sun, Thanh Nguyen, Mohamad Abdalkader, Wenhuo Chen, Xiaoxi Yao, Guangxiong Yuan, Tingyu Yi, Hongxin Han, Yuesong Pan, Tudor G Jovin, David S Liebeskind, Liping Liu, Xingquan Zhao, Zeguang Ren, Yilong Wang, Yongjun Wang, Bernard Yan, Zhongrong Miao
Stroke and Vascular Neurology Oct 2024, svn-2024-003318; DOI: 10.1136/svn-2024-003318
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Intra-arterial tenecteplase after successful endovascular therapy (ANGEL-TNK): protocol of a multicentre, open-label, blinded end-point, prospective, randomised trial
Xiaochuan Huo, Gang Luo, Dapeng Sun, Thanh Nguyen, Mohamad Abdalkader, Wenhuo Chen, Xiaoxi Yao, Guangxiong Yuan, Tingyu Yi, Hongxin Han, Yuesong Pan, Tudor G Jovin, David S Liebeskind, Liping Liu, Xingquan Zhao, Zeguang Ren, Yilong Wang, Yongjun Wang, Bernard Yan, Zhongrong Miao
Stroke and Vascular Neurology Oct 2024, svn-2024-003318; DOI: 10.1136/svn-2024-003318
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