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Rationale and design of the GOLDEN BRIDGE II: a cluster-randomised multifaceted intervention trial of an artificial intelligence-based cerebrovascular disease clinical decision support system to improve stroke outcomes and care quality in China

Zixiao Li, Xinmiao Zhang, Lingling Ding, Jing Jing, Hong-Qiu Gu, Yong Jiang, Xia Meng, Chunying Du, Chunjuan Wang, Meng Wang, Man Xu, Yanxu Zhang, Meera Hu, Hao Li, Xiping Gong, Kehui Dong, Xingquan Zhao, Yilong Wang, Liping Liu, Ying Xian, Eric Peterson, Gregg C Fonarow, Lee H Schwamm, Yongjun Wang
DOI: 10.1136/svn-2023-002411 Published 12 September 2023
Zixiao Li
1Department of Neurology, Beijing Tiantan Hospital, Beijing, China
2China National Clinical Research Center for Neurological Diseases, Beijing, China
3Chinese Institute for Brain Research, Beijing, China
4Research Unit of Artificial Intelligence in Cerebrovascular Disease, Chinese Academy of Medical Sciences, Beijing, China
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  • ORCID record for Zixiao Li
Xinmiao Zhang
1Department of Neurology, Beijing Tiantan Hospital, Beijing, China
2China National Clinical Research Center for Neurological Diseases, Beijing, China
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Lingling Ding
1Department of Neurology, Beijing Tiantan Hospital, Beijing, China
2China National Clinical Research Center for Neurological Diseases, Beijing, China
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Jing Jing
1Department of Neurology, Beijing Tiantan Hospital, Beijing, China
2China National Clinical Research Center for Neurological Diseases, Beijing, China
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Hong-Qiu Gu
2China National Clinical Research Center for Neurological Diseases, Beijing, China
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Yong Jiang
2China National Clinical Research Center for Neurological Diseases, Beijing, China
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Xia Meng
1Department of Neurology, Beijing Tiantan Hospital, Beijing, China
2China National Clinical Research Center for Neurological Diseases, Beijing, China
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Chunying Du
2China National Clinical Research Center for Neurological Diseases, Beijing, China
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Chunjuan Wang
1Department of Neurology, Beijing Tiantan Hospital, Beijing, China
2China National Clinical Research Center for Neurological Diseases, Beijing, China
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Meng Wang
2China National Clinical Research Center for Neurological Diseases, Beijing, China
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Man Xu
5Hanalytics Artificial Intelligence Research Centre for Neurological Disorders, China National Clinical Research Center for Neurological Diseases, Beijing, China
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Yanxu Zhang
5Hanalytics Artificial Intelligence Research Centre for Neurological Disorders, China National Clinical Research Center for Neurological Diseases, Beijing, China
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Meera Hu
5Hanalytics Artificial Intelligence Research Centre for Neurological Disorders, China National Clinical Research Center for Neurological Diseases, Beijing, China
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Hao Li
2China National Clinical Research Center for Neurological Diseases, Beijing, China
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Xiping Gong
1Department of Neurology, Beijing Tiantan Hospital, Beijing, China
2China National Clinical Research Center for Neurological Diseases, Beijing, China
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Kehui Dong
1Department of Neurology, Beijing Tiantan Hospital, Beijing, China
2China National Clinical Research Center for Neurological Diseases, Beijing, China
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Xingquan Zhao
1Department of Neurology, Beijing Tiantan Hospital, Beijing, China
2China National Clinical Research Center for Neurological Diseases, Beijing, China
4Research Unit of Artificial Intelligence in Cerebrovascular Disease, Chinese Academy of Medical Sciences, Beijing, China
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Yilong Wang
1Department of Neurology, Beijing Tiantan Hospital, Beijing, China
2China National Clinical Research Center for Neurological Diseases, Beijing, China
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Liping Liu
1Department of Neurology, Beijing Tiantan Hospital, Beijing, China
2China National Clinical Research Center for Neurological Diseases, Beijing, China
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Ying Xian
6Department of Neurology, The University of Texas Southwestern Medical Center, Dallas, Texas, USA
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Eric Peterson
7Division of Cardiology, Department of Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA
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Gregg C Fonarow
8Cardiology, Ronald Reagan UCLA Medical Center, Los Angeles, California, USA
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Lee H Schwamm
9Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA
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Yongjun Wang
1Department of Neurology, Beijing Tiantan Hospital, Beijing, China
2China National Clinical Research Center for Neurological Diseases, Beijing, China
4Research Unit of Artificial Intelligence in Cerebrovascular Disease, Chinese Academy of Medical Sciences, Beijing, China
10Clinical Center for Precision Medicine in Stroke, Capital Medical Universit, Beijing, China
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Article Information

DOI 
https://doi.org/10.1136/svn-2023-002411
PubMed 
37699726

Print ISSN 
2059-8688
Online ISSN 
2059-8696
History 
  • Received February 20, 2023
  • Accepted August 11, 2023
  • Published online September 12, 2023.

Article Versions

  • You are currently viewing a Previous version of this article (September 12, 2023 - 16:16).
  • latest version (February 2, 2024 - 07:55).
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Copyright & Usage 
© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

Author Information

  1. Zixiao Li1,2,3,4,
  2. Xinmiao Zhang1,2,
  3. Lingling Ding1,2,
  4. Jing Jing1,2,
  5. Hong-Qiu Gu2,
  6. Yong Jiang2,
  7. Xia Meng1,2,
  8. Chunying Du2,
  9. Chunjuan Wang1,2,
  10. Meng Wang2,
  11. Man Xu5,
  12. Yanxu Zhang5,
  13. Meera Hu5,
  14. Hao Li2,
  15. Xiping Gong1,2,
  16. Kehui Dong1,2,
  17. Xingquan Zhao1,2,4,
  18. Yilong Wang1,2,
  19. Liping Liu1,2,
  20. Ying Xian6,
  21. Eric Peterson7,
  22. Gregg C Fonarow8,
  23. Lee H Schwamm9,
  24. Yongjun Wang1,2,4,10
  1. 1Department of Neurology, Beijing Tiantan Hospital, Beijing, China
  2. 2China National Clinical Research Center for Neurological Diseases, Beijing, China
  3. 3Chinese Institute for Brain Research, Beijing, China
  4. 4Research Unit of Artificial Intelligence in Cerebrovascular Disease, Chinese Academy of Medical Sciences, Beijing, China
  5. 5Hanalytics Artificial Intelligence Research Centre for Neurological Disorders, China National Clinical Research Center for Neurological Diseases, Beijing, China
  6. 6Department of Neurology, The University of Texas Southwestern Medical Center, Dallas, Texas, USA
  7. 7Division of Cardiology, Department of Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA
  8. 8Cardiology, Ronald Reagan UCLA Medical Center, Los Angeles, California, USA
  9. 9Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA
  10. 10Clinical Center for Precision Medicine in Stroke, Capital Medical Universit, Beijing, China
  1. Correspondence to Dr Yongjun Wang; yongjunwang{at}ncrcnd.org.cn; Dr Zixiao Li; lizixiao2008{at}hotmail.com
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Rationale and design of the GOLDEN BRIDGE II: a cluster-randomised multifaceted intervention trial of an artificial intelligence-based cerebrovascular disease clinical decision support system to improve stroke outcomes and care quality in China
Zixiao Li, Xinmiao Zhang, Lingling Ding, Jing Jing, Hong-Qiu Gu, Yong Jiang, Xia Meng, Chunying Du, Chunjuan Wang, Meng Wang, Man Xu, Yanxu Zhang, Meera Hu, Hao Li, Xiping Gong, Kehui Dong, Xingquan Zhao, Yilong Wang, Liping Liu, Ying Xian, Eric Peterson, Gregg C Fonarow, Lee H Schwamm, Yongjun Wang
Stroke and Vascular Neurology Sep 2023, svn-2023-002411; DOI: 10.1136/svn-2023-002411

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Rationale and design of the GOLDEN BRIDGE II: a cluster-randomised multifaceted intervention trial of an artificial intelligence-based cerebrovascular disease clinical decision support system to improve stroke outcomes and care quality in China
Zixiao Li, Xinmiao Zhang, Lingling Ding, Jing Jing, Hong-Qiu Gu, Yong Jiang, Xia Meng, Chunying Du, Chunjuan Wang, Meng Wang, Man Xu, Yanxu Zhang, Meera Hu, Hao Li, Xiping Gong, Kehui Dong, Xingquan Zhao, Yilong Wang, Liping Liu, Ying Xian, Eric Peterson, Gregg C Fonarow, Lee H Schwamm, Yongjun Wang
Stroke and Vascular Neurology Sep 2023, svn-2023-002411; DOI: 10.1136/svn-2023-002411
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Rationale and design of the GOLDEN BRIDGE II: a cluster-randomised multifaceted intervention trial of an artificial intelligence-based cerebrovascular disease clinical decision support system to improve stroke outcomes and care quality in China
Zixiao Li, Xinmiao Zhang, Lingling Ding, Jing Jing, Hong-Qiu Gu, Yong Jiang, Xia Meng, Chunying Du, Chunjuan Wang, Meng Wang, Man Xu, Yanxu Zhang, Meera Hu, Hao Li, Xiping Gong, Kehui Dong, Xingquan Zhao, Yilong Wang, Liping Liu, Ying Xian, Eric Peterson, Gregg C Fonarow, Lee H Schwamm, Yongjun Wang
Stroke and Vascular Neurology Sep 2023, svn-2023-002411; DOI: 10.1136/svn-2023-002411
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