Article Figures & Data
Tables
- Table 1
Patient, disease and treatment characteristics
Categorical and dichotomous variables Whole cohort Femoral Radial Pearson χ2 Pre-stroke independence (mRS 0–2) 90.1% (338/375) 88.2% (216/245) 93.8% (122/130) OR 2.05 (0.91–4.62) p=0.079 Operator three performing procedure 35.2% (132/375) 6.1% (15/245) 90 .% (117/130) OR 138 (64–300) p=0.000 Wake-up stroke/onset unknown 31.5% (118/375) 29.8% (73/245) 34.6% (45/130) OR 1.25 (0.79–1.96) p=0.339 Female 50.7% (190/375) 51.4% (126/245) 49.2% (64/130) OR 0.92 (0.60–1.40) p=0.685 Use of CTA 95.7% (359/375) 96.3% (236/245) 94.6% (123/130) OR 0.67 (0.24–1.84) p=0.435 Use of CTP 65.6% (246/375) 66.1% (162/245) 64.6% (84/130) OR 0.94 (0.60–1.46) p=0.770 Intracranial large vessel occlusion site Internal Carotid Artery 24.3% (91/375) 22.4% (55/245) 27.7% (36/130) Middle Cerebral Artery M1 segment 52 .% (195/375) 51 .% (125/245) 53.8% (70/130) Middle Cerebral Artery M2 segment 23.5% (88/375) 26.1% (64/245) 18.5% (24/130) Aneterior Cerebral Artery 0.3% (1/375) 0.4% (1/245) 0 .% (0/130) P=0.290 *Cochran–Mantel IV TPA prior to MT 9.9% (37/375) 11.8% (29/245) 6.2% (8/130) OR 0.49 (0.22–1.10) p=0.079 GA 89.9% (337/375) 91.4% (224/245) 86.9% (113/130) OR 0.62 (0.32–1.23) p=0.169 GA induction before arteriotomy 35.9% (121/337) 29.9% (67/224) 47.8% (54/113) OR 2.14 (1.34–3.42) p=0.001 Aspiration only (no stent-retriever) 34.9% (131/375) 31.4% (77/245) 41.5% (54/130) OR 0.65 (0.42–1.00) p=0.051 Carotid stenting 16 .% (60/375) 14.7% (36/245) 18.5% (24/130) OR 1.31 (0.75–2.32) p=0.344 Intracranial stenting 5.6% (21/375) 4.9% (12/245) 6.9% (9/130) OR 1.44 (0.59–3.52) p=0.417 Continuous variables—median (IQR) Whole cohort Femoral Radial Mann-Whitney U test Age 75 (64–84) 76 (64–85) 74 (62–83) P=0.375 NIHSS 14 (8.5–19) 14 (8–19) 15 (10–19) P=0.231 RACE 6 (3.5–8) 6 (3–8) 6 (5–8) P=0.140 ASPECTS 9 (8–10) 9 (8–10) 9 (8–10) P=0.053 Onset/last known normal to ER presentation (mins) 120 (65–401) 110 (63.5–321) 150 (65.5–602) P=0.103 ER presentation to CT (min) 17 (12–29) 17 (12–27) 18 (12–34) P=0.515 CT to arteriotomy (min) 59.5 (37–84) 58.5 (35–85) 60 (40–84) P=0.777 Arteriotomy to reperfusion (min) 29 (19–46.5) 30 (20–40) 25 (17–43) P=0.036 CT to reperfusion (min) 95.5 (70–126.5) 96.5 (71–130) 95 (68–123) P=0.456 Days in MT hospital 4 (2–8) 4 (2–8) 4 (2–7) P=0.888 ER, emergency room; GA, general anaesthesia; ICA, internal carotid artery; IV, intravenous; mRS, modified Rankin score; MT, mechanical thrombectomy.
- Table 2
Primary outcomes
Primary outcomes Whole cohort Femoral Radial Pearson χ2/Mann-Whitney U test mRS 0–2 at 90 days
(in patients with prestroke mRS 0–2)61.3% (206/336) 57.9% (124/214) 67.2% (82/122) OR 1.49 (95% CI 0.93 to 2.37) p=0.092 CT to reperfusion
(median (IQR) min)95.5 (70–126.5) 96.5 (71–130) 95 (68–123) P=0.456 - Table 3
Secondary outcomes
Categorical and dichotomous variables Whole cohort Femoral Radial Pearson χ2 Arteriotomy cross-over 2.7% (10/375) 1.6% (4/245) 4.6% (6/130) OR 2.92 (0.81–10.52) p=0.088 First pass reperfusion 54.7% (205/375) 55.5% (136/245) 53.1% (69/130) OR 0.91 (0.59–1.39) p=0.652 Final angiographic result=eTICI 2B-3 94.4% (354/375) 94.3% (231/245) 94.6% (123/130) OR 1.06 (0.42–2.71) p=0.895 sICH 4 .% (15/375) 4.9% (12/245) 2.3% (3/130) OR 0.46 (0.13–1.66) p=0.223 Access site complication requiring additional procedure 4.3% (16/375) 6.5% (16/245) 0% (0/130) p=0.003 mRS 0–2 at 90 days
(in patients with pre-stroke mRS 0–2)61.3% (206/336) 57.9% (124/214) 67.2% (82/122) OR 1.49 (0.93–2.37) p=0.092 Continuous variables - medians (IQR) Whole cohort Femoral Radial Mann-Whitney U Test CT to arteriotomy 59.5 (37–84) 58.5 (35–85) 60 (40–84) P=0.777 Arteriotomy to reperfusion 29 (19–46.5) 30 (20–40) 25 (17–43) P=0.036 CT to reperfusion 95.5 (70–126.5) 96.5 (71–130) 95 (68–123) P=0.456 Days in MT hospital 4 (2–8) 4 (2–8) 4 (2–7) P=0.888 mRS, modified Rankin score; MT, mechanical thrombectomy; sICH, symptomatic intracranial haemorrhage.