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Cilostazol and isosorbide mononitrate for the prevention of progression of cerebral small vessel disease: baseline data and statistical analysis plan for the Lacunar Intervention Trial-2 (LACI-2) (ISRCTN14911850)

Philip M Bath, Iris Mhlanga, Lisa J Woodhouse, Fergus Doubal, Katherine Oatey, Alan A Montgomery, Joanna M Wardlaw
DOI: 10.1136/svn-2022-001816 Published 25 April 2023
Philip M Bath
1 Stroke Trials Unit, University of Nottingham, Nottingham, UK
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Iris Mhlanga
1 Stroke Trials Unit, University of Nottingham, Nottingham, UK
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Lisa J Woodhouse
1 Stroke Trials Unit, University of Nottingham, Nottingham, UK
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Fergus Doubal
2 Centre for Clinical Brain Sciences, UK Dementia Research Institute Centre, University of Edinburgh, Edinburgh, UK
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Katherine Oatey
3 Edinburgh Clinical Trials Unit, University of Edinburgh, Edinburgh, UK
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Alan A Montgomery
4 Nottingham Clinical Trials Unit, University of Nottingham, Nottingham, UK
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Joanna M Wardlaw
2 Centre for Clinical Brain Sciences, UK Dementia Research Institute Centre, University of Edinburgh, Edinburgh, UK
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Article Information

vol. 8 no. 2 134-143
DOI 
https://doi.org/10.1136/svn-2022-001816
PubMed 
36219567

Print ISSN 
2059-8688
Online ISSN 
2059-8696
History 
  • Received June 29, 2022
  • Accepted August 16, 2022
  • Published online April 25, 2023.

Article Versions

  • Previous version (September 2, 2022 - 06:34).
  • Previous version (September 27, 2022 - 08:23).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

Author Information

  1. Philip M Bath1,
  2. Iris Mhlanga1,
  3. Lisa J Woodhouse1,
  4. Fergus Doubal2,
  5. Katherine Oatey3,
  6. Alan A Montgomery4,
  7. Joanna M Wardlaw2
  8. LACI-2 Trial Investigators
  1. 1 Stroke Trials Unit, University of Nottingham, Nottingham, UK
  2. 2 Centre for Clinical Brain Sciences, UK Dementia Research Institute Centre, University of Edinburgh, Edinburgh, UK
  3. 3 Edinburgh Clinical Trials Unit, University of Edinburgh, Edinburgh, UK
  4. 4 Nottingham Clinical Trials Unit, University of Nottingham, Nottingham, UK
  1. Correspondence to Professor Philip M Bath; philip.bath{at}nottingham.ac.uk
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Vol 8 Issue 2 Table of Contents
Stroke and Vascular Neurology: 8 (2)
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Cilostazol and isosorbide mononitrate for the prevention of progression of cerebral small vessel disease: baseline data and statistical analysis plan for the Lacunar Intervention Trial-2 (LACI-2) (ISRCTN14911850)
Philip M Bath, Iris Mhlanga, Lisa J Woodhouse, Fergus Doubal, Katherine Oatey, Alan A Montgomery, Joanna M Wardlaw
Stroke and Vascular Neurology Apr 2023, 8 (2) 134-143; DOI: 10.1136/svn-2022-001816

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Cilostazol and isosorbide mononitrate for the prevention of progression of cerebral small vessel disease: baseline data and statistical analysis plan for the Lacunar Intervention Trial-2 (LACI-2) (ISRCTN14911850)
Philip M Bath, Iris Mhlanga, Lisa J Woodhouse, Fergus Doubal, Katherine Oatey, Alan A Montgomery, Joanna M Wardlaw
Stroke and Vascular Neurology Apr 2023, 8 (2) 134-143; DOI: 10.1136/svn-2022-001816
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Cilostazol and isosorbide mononitrate for the prevention of progression of cerebral small vessel disease: baseline data and statistical analysis plan for the Lacunar Intervention Trial-2 (LACI-2) (ISRCTN14911850)
Philip M Bath, Iris Mhlanga, Lisa J Woodhouse, Fergus Doubal, Katherine Oatey, Alan A Montgomery, Joanna M Wardlaw
Stroke and Vascular Neurology Apr 2023, 8 (2) 134-143; DOI: 10.1136/svn-2022-001816
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