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Analytical validation of GMEX rapid point-of-care CYP2C19 genotyping system for the CHANCE-2 trial

Xia Meng, Anxin Wang, Guojun Zhang, Siying Niu, Wei Li, Sifei Han, Fang Fang, Xingquan Zhao, Kehui Dong, Zening Jin, Huaguang Zheng, Kelin Chen, Hao Li, Chengyuan Yang, Yongjun Wang
DOI: 10.1136/svn-2021-000874 Published 28 June 2021
Xia Meng
1 China National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
2 Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
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Anxin Wang
1 China National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
2 Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
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  • ORCID record for Anxin Wang
Guojun Zhang
3 Department of Clinical Diagnosis Laboratory, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
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Siying Niu
1 China National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
2 Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
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Wei Li
1 China National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
2 Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
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Sifei Han
4 Biomedical and Health Informatics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
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Fang Fang
1 China National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
2 Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
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Xingquan Zhao
1 China National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
2 Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
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Kehui Dong
1 China National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
2 Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
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Zening Jin
5 Department of Cardiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
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Huaguang Zheng
1 China National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
2 Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
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Kelin Chen
3 Department of Clinical Diagnosis Laboratory, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
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Hao Li
1 China National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
2 Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
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Chengyuan Yang
1 China National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
2 Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
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Yongjun Wang
1 China National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
2 Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
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Article Information

vol. 6 no. 2 274-279
DOI 
https://doi.org/10.1136/svn-2021-000874
PubMed 
33952669

Print ISSN 
2059-8688
Online ISSN 
2059-8696
History 
  • Received January 13, 2021
  • Revised March 25, 2021
  • Accepted April 8, 2021
  • Published online June 28, 2021.

Article Versions

  • Previous version (May 5, 2021 - 01:55).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

Author Information

  1. Xia Meng1,2,
  2. Anxin Wang1,2,
  3. Guojun Zhang3,
  4. Siying Niu1,2,
  5. Wei Li1,2,
  6. Sifei Han4,
  7. Fang Fang1,2,
  8. Xingquan Zhao1,2,
  9. Kehui Dong1,2,
  10. Zening Jin5,
  11. Huaguang Zheng1,2,
  12. Kelin Chen3,
  13. Hao Li1,2,
  14. Chengyuan Yang1,2,
  15. Yongjun Wang1,2
  1. 1 China National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
  2. 2 Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
  3. 3 Department of Clinical Diagnosis Laboratory, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
  4. 4 Biomedical and Health Informatics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
  5. 5 Department of Cardiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
  1. Correspondence to Dr Yongjun Wang; yongjunwang{at}ncrcnd.org.cn
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Analytical validation of GMEX rapid point-of-care CYP2C19 genotyping system for the CHANCE-2 trial
Xia Meng, Anxin Wang, Guojun Zhang, Siying Niu, Wei Li, Sifei Han, Fang Fang, Xingquan Zhao, Kehui Dong, Zening Jin, Huaguang Zheng, Kelin Chen, Hao Li, Chengyuan Yang, Yongjun Wang
Stroke and Vascular Neurology Jun 2021, 6 (2) 274-279; DOI: 10.1136/svn-2021-000874

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Analytical validation of GMEX rapid point-of-care CYP2C19 genotyping system for the CHANCE-2 trial
Xia Meng, Anxin Wang, Guojun Zhang, Siying Niu, Wei Li, Sifei Han, Fang Fang, Xingquan Zhao, Kehui Dong, Zening Jin, Huaguang Zheng, Kelin Chen, Hao Li, Chengyuan Yang, Yongjun Wang
Stroke and Vascular Neurology Jun 2021, 6 (2) 274-279; DOI: 10.1136/svn-2021-000874
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Analytical validation of GMEX rapid point-of-care CYP2C19 genotyping system for the CHANCE-2 trial
Xia Meng, Anxin Wang, Guojun Zhang, Siying Niu, Wei Li, Sifei Han, Fang Fang, Xingquan Zhao, Kehui Dong, Zening Jin, Huaguang Zheng, Kelin Chen, Hao Li, Chengyuan Yang, Yongjun Wang
Stroke and Vascular Neurology Jun 2021, 6 (2) 274-279; DOI: 10.1136/svn-2021-000874
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