Article Figures & Data
- Figure 1
Illustration of recanalisation versus persistent vessel occlusion in two patients. Both patients presented with a low Alberta Stroke Program Early CT Score (ASPECTS) and poor collateral status at admission. The patient in the upper row did not undergo endovascular treatment and exhibited a significantly aggravated oedema formation in follow-up imaging. The patient in the lower row presented with an even lower ASPECTS of 3, but showed less oedema formation in follow-up imaging. CTA,CT angiography; MIP, maximum intensity projection; NECT, non-enhanced CT; NMU,net water uptake.
- Figure 2
Regression analyses for clinical outcome and lesion pathophysiology. The impact of endovascular recanalisation in patients with poor intracranial collaterals (X axis) on modified ranking scale (mRS) score at 90 days (left), ischaemic lesion water uptake (middle) and total lesion volume (right) based on multivariable linear regression analysis. Ordinal mRS values were treated as scaled variable for linear regression. FCT, follow-up CT.
- Figure 3
Clinical outcome, quantitative lesion water uptake and total lesion volume in the study cohort. Boxplots to illustrate differences in clinical outcome, indicated by modified ranking scale scores (mRS) at 90 days (left), per cent lesion water uptake in follow-up CT (FCT, middle) and total lesion volume (right) in patients with successful vessel recanalisation versus persistent vessel occlusion. NWU, netwater uptake.
- Table 1
Characteristics of patients with poor collaterals (n=129)
Patient characteristics Vessel
recanalisationPersistent vessel
occlusionGroup comparison
P valueSubjects, n (%) 87 (67) 42 (33) na Age in years, median (IQR) 76 (65–82) 73 (69–84) 0.62 Female sex, n (%) 36 (42) 17 (41) 0.89 Admission NIHSS, median (IQR) 17 (15–20) 19 (17–20) 0.03 ASPECTS, median (IQR) 6 (5–8) 4 (3–5) <0.001 Time onset to imaging in hours, mean (SD) 2.9 (2.1) 3.7 (1.6) 0.03 Mechanical thrombectomy, n (%) 87 (100) 17 (41) <0.01 Collateral Score, median (IQR) 1 (1–2) 1 (0–1) 0.003 Initial NWU in %, mean (SD) 11.0 (5.6) 10.6 (4.3) 0.69 Follow-up endpoints Follow-up infarct volume in mL, median (IQR) 35 (13-129) 150 (90-206) <0.001 Follow-up NWU in %, mean (SD) 19.5 (6.0) 26.8 (6.4) <0.001 mRS, median (IQR)* 4.5 (2–6) 5 (5–6) <0.001 mRS 0–2, n (%) 23 (26) 1 (2) <0.001 mRS 3–4, n (%) 19 (22) 7 (17) 1.0 mRS 5–6, n (%) 42 (48) 33 (79) <0.001 *mRS score not available, n 3 1 mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale; NWU, net water uptake.
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Supplementary Data
This web only file has been produced by the BMJ Publishing Group from an electronic file supplied by the author(s) and has not been edited for content.
Supplementary Data
This web only file has been produced by the BMJ Publishing Group from an electronic file supplied by the author(s) and has not been edited for content.
