Article Figures & Data
Figures
- Figure 1
ROC curve of SII, PLR and NLR in acute/subacute Patients with CVST. CVST, cerebral venous sinus thrombosis; NLR, neutrophil to lymphocyte ratio; PLR, platelet to lymphocyte ratio; ROC, Receiver Operating Curve; SII, systemic immune–inflammation index.
- Figure 2
Kaplan-Meier analysis for acute/subacute patients with CVST with higher/lower SII. CVST, cerebral venous sinus thrombosis; SII, systemic immune–inflammation index.
- Figure 3
Cox regression analysis of overall survival in acute/subacute patients with CVST. CVST, cerebral venous sinus thrombosis; SII, systemic immune–inflammation index.
Tables
- Table 1
Demographic and clinical characteristics of the two outcomes groups in acute/subacute patients with CVST
Variable Total Good (239, 89.0%) Poor (31, 11.0 %) P value Age 34.50±13.12 33.36±12.49 42.00±14.84 0.002* Gender 270 239 31 0.044* Female 156 134 22 Male 114 105 9 Malignancy 4 3 1 0.575 Infection 57 48 9 0.511 Pregnancy or puerperium 65 53 12 0.518 Intracerebral haemorrhage 62 53 9 0.674 Coma 72 50 22 <0.001* Mental disorder 15 10 5 0.303 Lymphocyte 1.67±0.84 1.74±0.85 1.19±0.62 <0.001* Granulocyte 7.27±4.73 7.04±4.63 8.79±5.15 0.066 Platelet 244.12±124.21 243.15±122.08 250.54±139.23 0.768 PLR 179.47±129.72 159.61±90.38 339.32±257.80 <0.001* NLR 6.81±7.90 5.50±5.15 17.05±15.94 <0.001* SII 1380.86±1763.22 1151.71±1085.54 2893.31±3680.81 <0.001* Left sigmoid sinus 70 47 23 0.629 Right sigmoid sinus 75 57 18 0.218 Left transverse sinus 98 63 35 0.147 Right transverse sinus 97 73 24 0.188 Straight sinus 21 14 7 0.011* Superior sagittal sinus 159 119 40 0.243 Inferior sagittal sinus 25 13 12 0.061 Torcular 28 18 10 0.510 Deep cerebral venous 8 6 2 0.284 *Statistically significant.
CVST, cerebral venous sinus thrombosis; NLR, neutrophil to lymphocyte ratio; PLR, platelet to lymphocyte ratio; SII, systemic immune–inflammation index.
- Table 2
Multivariable logistic regression analysis in different subgroups with acute/subacute patients with CVST
Groups Variable OR 95% CI P value Subgroup 1 Age 1.055 1.027 to 1.083 <0.001* SII 1.303 1.102 to 1.501 0.011* Coma 2.726 1.547 to 3.963 0.026* Straight sinus 2.485 1.142 to 5.409 0.022* Subgroup 2 Age 1.100 1.027 to 1.177 0.006* SII 1.104 0.998 to 1.209 0.251 Coma 2.667 1.196 to 5.209 0.001* Straight sinus 5.104 1.998 to 12.209 0.009* Subgroup 3 Age 1.216 0.862 to 1.715 0.266 SII 1.407 1.204 to 1.703 0.034* Coma 1.101 0.997 to 1.501 0.061 Straight sinus 5.412 0.769 to 11.436 0.120 Subgroup 4 Age 1.064 1.016 to 1.115 0.009* SII 1.207 0.986 to 1.505 0.119 Coma 4.753 2.082 to 6.834 0.003* Straight sinus 4.086 1.031 to 8.696 0.046* *Statistically significant. Subgroup analysis was carried out in male (subgroup 1), female (subgroup 2), pregnancy/puerperium (subgroup 3) and non-pregnancy/puerperium (subgroup 4) Patients with CVST.
CVST, cerebral venous sinus thrombosis; SII, systemic immune–inflammation index.
Supplementary data
