Article Figures & Data
- Figure 1
Sequential lodges by the 406 total emboli for the four anatomical conditions of the supra-aortic vessels tested. After fragmentation, the median number of lodgments per clot was four, with a minimum of 1 and a maximum of 8. The number indicated over each graphic (ranging from 1 to 8) is the sequential number of lodgments referred to in that chart. See the online supplemental table S1 for a more detailed description. ACA, anterior cerebral artery; ICA, internal carotid artery; MCA, middle cerebral artery; PCA, posterior cerebral artery.
- Figure 2
Sankey flow diagrams of sequential embolic lodgments by anatomical condition of the supra-aortic vessels. The diagram shows the flows and their relative quantities in proportion to each other. Vertical coloured lines represent each lodgment (first, second, third, etc). Horizontal flow lines represent the relative quantity of fragments anchored at a particular intracranial location after a specific prior clot allocation. Emboli that migrated to the opposite hemisphere are shown in blue. Emboli that travelled to the ipsilateral ACA are shown in green. (A) Baseline: supra-aortic vessels without occlusion (97 emboli from 29 injected clots); (B) Emboli from an occluded right CA (88/25); (C) Emboli through the right CA with occlusion of the left CA (122/24); (D) Emboli through the right CA with concomitant occlusion of both vertebral arteries (99/26). ACA, anterior cerebral artery; CA, carotid artery; ICA-T, terminal internal CA; MCA, middle cerebral artery; PCA, posterior cerebral artery.
- Table 1
Frequency of intracranial lodgment of clot fragments for the four SAV conditions tested
Embolus location Total emboli*
(n=406)Patent
SAV
(n=97)Ipsilateral CA occluded
(n=88)Contralateral CA occluded
(n=122)Vertebral arteries occluded
(n=99)P value Ipsilateral MCA 159
(39.2%)47
(48.5%)33
(37.5%)39
(32%)40
(40.4%)<0.0001 Ipsilateral A1 and A2 segments 99
(24.4%)28
(28.9%)14
(15.9%)30
(24.6%)27
(27.3%)Ipsilateral PCA 56
(13.8%)11
(11.3%)12
(13.6%)8
(6.6%)25
(25.3%)Contralateral MCA 33
(8.1%)0
–7
(8%)25
(20.5%)1
(1%)Contralateral A1 and A2 segments+ACoA 30
(7.4%)1
(1%)5
(5.7%)20
(16.4%)4
(4%)Floating ICA thrombus 16
(3.9%)6
(6.2%)10
(11.4%)0
–0
–Terminal ICA 11
(2.7%)4
(4.1%)5
(5.7%)0
–2
(2%)Contralateral PCA 2
(0.5%)0
–2
(2.3%)0
–0
–Markov Chain Monte Carlo estimated p value.
*Fragments of the same clot repeating an anchor location have also been included.
ACoA, anterior communicating artery; CA, carotid artery; MCA, middle cerebral artery; PCA, posterior cerebral artery; SAV, supra-aortic vessel.
Supplementary Materials
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Supplementary Data
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