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Flow diversion covering the M1 origin as a last resort

Li-Mei Lin, Matthew T Bender, Geoffrey P Colby, Bowen Jiang, Jessica K Campos, David A Zarrin, Robert W C Young, Risheng Xu, Justin M Caplan, Judy Huang, Rafael J Tamargo, Alexander L Coon
DOI: 10.1136/svn-2018-000204 Published 19 December 2018
Li-Mei Lin
1Department of Neurosurgery, University of California Irvine, Orange, California, USA
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Matthew T Bender
2Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
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Geoffrey P Colby
3Department of Neurosurgery, University of California Los Angeles, Los Angeles, California, USA
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Bowen Jiang
2Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
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Jessica K Campos
1Department of Neurosurgery, University of California Irvine, Orange, California, USA
2Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
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David A Zarrin
2Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
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Robert W C Young
2Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
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Risheng Xu
2Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
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Justin M Caplan
2Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
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Judy Huang
2Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
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Rafael J Tamargo
2Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
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Alexander L Coon
2Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
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    Figure 1

    Case 8: Cinquagenarian with (A,B) R ICA DSA showing growing residual of a previously coiled 8 mm right A1 aneurysm and (C) L CCA DSA showing absent ACoA. (D) Unsubtracted DSA during PED placement from R ACA into R ICA across M1 origin, which continued to fill anterograde, without delay, in parallel with the ACA at both (E) 6 months and (F) 12 months follow-up R ICA DSA. ACA, anterior cerebral artery; ACoA, anterior communicating artery; CCA, common carotid artery; DSA, digital subtraction angiography; ICA, internal carotid artery; PED, pipeline embolisation device.

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    Figure 2

    Case 5: Sexagenarian with (A) R CCA DSA showing absent ACoA and (B) L CCA DSA showing fusiform PCoA aneurysm with (C) dome irregularity and short postcommunicating landing zone in the ICA. (D) Treatment with single-stage pipeline with adjunctive coiling from the ACA into the ICA. (E) Immediate postprocedural DSA showing platelet aggregation at the M1 origin and delayed MCA filling when the patient awoke with right upper extremity (RUE) weakness (F) resolved clinically and improved angiographically after intra-arterial Abciximab administration. Follow-up DSA at (G) 2 months, (H) 6 months, (I) 12 months, after which Prasugrel was weaned and (J) 24 months showing progressive recruitment of pial collaterals from the ACA and ECA to supply the MCA territory and moderately delayed filling of the covered MCA in the parenchymal phase. ACA, anterior cerebral artery; ACoA, anterior communicating artery; CCA, common carotid artery; DSA, digital subtraction angiography; ECA, external carotid artery; ICA, internal carotid artery; MCA, middle cerebral artery; PCoA, posterior communicating artery.

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    Figure 3

    Case 1: Teenage patient with history of bicoronal craniotomy for craniopharyngioma resection followed by proton beam therapy who presented with (A) R ICA DSA showing 11 mm A1 aneurysm and (B) L CCA DSA showing hypoplastic left ACA. (C) 3-D rotational angiography shows fusiform and highly irregular morphology. (D) Unsubtracted DSA from treatment with single-stage pipeline with adjunctive coiling from R ACA into R ICA. Follow-up R CCA DSA at (E) 2 months shows dome occlusion of the aneurysm with residual neck filling and anterograde arterial phase filling of the jailed R MCA. (F) 6 months shows some ghosting across the M1, (G,H) increased ghosting at 12 months follow-up DSA after stopping Plavix with significant recruitment of pial collaterals from the ACA in the late arterial and parenchymal phase. (I) 24-month DSA arterial phase shows limited anterograde filling of the jailed MCA and (J) robust pial collaterals from ACA and ECA apparent on parenchymal phase runs. ACA, anterior cerebral artery; CCA, common carotid artery; DSA, digital subtraction angiography; ECA, external carotid artery; ICA, internal carotid artery; MCA, middle cerebral artery.

Tables

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  • Table 1: Case details
    Case no.Size (mm)SideMorphologyLocationClinical historyTreatmentComplicationsAneurysm occlusionMCA delay
    111RFusiformAh/o craniopharyngioma rsxn, proton beamPED+coil–CompleteSignificant
    26RFusiformPCoA, ICATh/o SAH, prev coil/recur ICAT, new PCoAPED–CompleteMinimal
    39LSaccularA1IncidentalPED+coilRetroperitoneal haematoma, L MCA stroke, mortality––-
    47RSaccularA1IncidentalPED–CompleteMinimal
    517LFusiformPCoAh/o SAH from ruptured ACoAPEDR paresis on emergence; DSA M1 platelet plug; resolved with ReoproDome occlusion/
    neck residual
    Moderate
    63RSaccularA1IncidentalPEDPost-embo hypotensions, MCA ischaemia, residual LUE weakness (mRS=2)CompleteSignificant
    74RSaccularA1IncidentalPED–CompleteModerate
    88RSaccularICATh/o coiling, recanalisationPED–CompleteMinimal
    910RPseudoaneurysmPCoATraumatic ICA injuryPEDIntraprocedural platelet aggregation, resolved with ReoproCompleteMinimal
    • DSA, digital subtraction angiography; ICAT, internal carotid artery termination; MCA, middle cerebral artery; PCoA, posterior communicating artery; PED, pipeline embolisation device.

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Stroke and Vascular Neurology: 10 (1)
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Flow diversion covering the M1 origin as a last resort
Li-Mei Lin, Matthew T Bender, Geoffrey P Colby, Bowen Jiang, Jessica K Campos, David A Zarrin, Robert W C Young, Risheng Xu, Justin M Caplan, Judy Huang, Rafael J Tamargo, Alexander L Coon
Stroke and Vascular Neurology Dec 2018, svn-2018-000204; DOI: 10.1136/svn-2018-000204

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Flow diversion covering the M1 origin as a last resort
Li-Mei Lin, Matthew T Bender, Geoffrey P Colby, Bowen Jiang, Jessica K Campos, David A Zarrin, Robert W C Young, Risheng Xu, Justin M Caplan, Judy Huang, Rafael J Tamargo, Alexander L Coon
Stroke and Vascular Neurology Dec 2018, svn-2018-000204; DOI: 10.1136/svn-2018-000204
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Flow diversion covering the M1 origin as a last resort
Li-Mei Lin, Matthew T Bender, Geoffrey P Colby, Bowen Jiang, Jessica K Campos, David A Zarrin, Robert W C Young, Risheng Xu, Justin M Caplan, Judy Huang, Rafael J Tamargo, Alexander L Coon
Stroke and Vascular Neurology Dec 2018, svn-2018-000204; DOI: 10.1136/svn-2018-000204
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