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Reteplase versus alteplase for acute ischaemic stroke within 4.5 hours (RAISE): rationale and design of a multicentre, prospective, randomised, open-label, blinded-endpoint, controlled phase 3 non-inferiority trial

Shuya Li, Hong-Qiu Gu, Hongguo Dai, Guozhi Lu, Yongjun Wang
DOI: 10.1136/svn-2023-003035 Published 5 November 2024
Shuya Li
1 Department of Neurology, and Department of Clinical Trial Center, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
2 China National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
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Hong-Qiu Gu
1 Department of Neurology, and Department of Clinical Trial Center, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
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Hongguo Dai
3 Department of Emergency, Linfen Central Hospital, Shanxi Province, China
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Guozhi Lu
4 Department of Neurology, Keshiketeng Banner Traditional Chinese Medicine Mongolian Medical Hospital, The Inner Mongolia autonomous region, China
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Yongjun Wang
1 Department of Neurology, and Department of Clinical Trial Center, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
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Article Information

vol. 9 no. 5 568-573
DOI 
https://doi.org/10.1136/svn-2023-003035
PubMed 
38286482

Print ISSN 
2059-8688
Online ISSN 
2059-8696
History 
  • Received December 10, 2023
  • Accepted December 23, 2023
  • Published online November 5, 2024.

Article Versions

  • Previous version (January 29, 2024 - 06:24).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

Author Information

  1. Shuya Li1,2,
  2. Hong-Qiu Gu1,
  3. Hongguo Dai3,
  4. Guozhi Lu4,
  5. Yongjun Wang1
  1. 1 Department of Neurology, and Department of Clinical Trial Center, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
  2. 2 China National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
  3. 3 Department of Emergency, Linfen Central Hospital, Shanxi Province, China
  4. 4 Department of Neurology, Keshiketeng Banner Traditional Chinese Medicine Mongolian Medical Hospital, The Inner Mongolia autonomous region, China
  1. Correspondence to Dr Yongjun Wang; yongjunwang{at}ncrcnd.org.cn
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Reteplase versus alteplase for acute ischaemic stroke within 4.5 hours (RAISE): rationale and design of a multicentre, prospective, randomised, open-label, blinded-endpoint, controlled phase 3 non-inferiority trial
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Reteplase versus alteplase for acute ischaemic stroke within 4.5 hours (RAISE): rationale and design of a multicentre, prospective, randomised, open-label, blinded-endpoint, controlled phase 3 non-inferiority trial
Shuya Li, Hong-Qiu Gu, Hongguo Dai, Guozhi Lu, Yongjun Wang
Stroke and Vascular Neurology Oct 2024, 9 (5) 568-573; DOI: 10.1136/svn-2023-003035

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Reteplase versus alteplase for acute ischaemic stroke within 4.5 hours (RAISE): rationale and design of a multicentre, prospective, randomised, open-label, blinded-endpoint, controlled phase 3 non-inferiority trial
Shuya Li, Hong-Qiu Gu, Hongguo Dai, Guozhi Lu, Yongjun Wang
Stroke and Vascular Neurology Oct 2024, 9 (5) 568-573; DOI: 10.1136/svn-2023-003035
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Reteplase versus alteplase for acute ischaemic stroke within 4.5 hours (RAISE): rationale and design of a multicentre, prospective, randomised, open-label, blinded-endpoint, controlled phase 3 non-inferiority trial
Shuya Li, Hong-Qiu Gu, Hongguo Dai, Guozhi Lu, Yongjun Wang
Stroke and Vascular Neurology Oct 2024, 9 (5) 568-573; DOI: 10.1136/svn-2023-003035
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