Article Figures & Data
Figures
- Figure 1
Forest plot of haemorrhagic events. (A) Forest plot of all bleeding events; (B) Forest plot of intracranial haemorrhage; (C) Forest plot of severe or moderate bleeding events; (D) Forest plot of fatal bleeding events. A, aspirin; C+A, clopidogrel plus aspirin; T+A, ticagrelor plus aspirin; CHANCE 2, Ticagrelor or Clopidogrel with Aspirin in High-Risk Patients with Acute Nondisabling Cerebrovascular Events II; PRINCE, Platelet Reactivity in Acute Stroke or Transient Ischaemic Attack; THALES, Ticagrelor and ASA for Prevention of Stroke and Death; RR, raletive risk; CI, Confidence Interval.
- Figure 2
Forest plot of stroke events. (A) Forest plot of stroke recurrence; (B) forest plot of TIA recurrence. A, aspirin; C+A, clopidogrel plus aspirin; T+A, ticagrelor plus aspirin; CHANCE 2, Ticagrelor or Clopidogrel with Aspirin in High-Risk Patients with Acute Nondisabling Cerebrovascular Events II ; PRINCE, Platelet Reactivity in Acute Stroke or Transient Ischaemic Attack; THALES, Ticagrelor and ASA for Prevention of Stroke and Death; TIA, transient ischaemic attack; RR, raletive risk; CI, Confidence Interval.
- Figure 3
Forest plot of death. A, aspirin; C+A, clopidogrel plus aspirin; T+A, ticagrelor plus aspirin; CHANCE 2, Ticagrelor or Clopidogrel with Aspirin in High-Risk Patients with Acute Nondisabling Cerebrovascular Events II; PRINCE, Platelet Reactivity in Acute Stroke or Transient Ischaemic Attack; THALES, Ticagrelor and ASA for Prevention of Stroke and Death; RR, raletive risk; CI, Confidence Interval.
Tables
- Table 1
The intervention of ticagrelor related stroke trials
Trails Intervention Control Duration THALES Ticagrelor 180 mg loading dose followed by 90 mg two times per day plus aspirin Aspirin 30 days PRINCE Ticagrelor 180 mg loading dose followed by 90 mg two times per day plus aspirin Clopidogrel 300 mg loading dose followed by 75 mg daily plus aspirin 21 days CHANCE 2 Ticagrelor 180 mg loading dose followed by 90 mg two times per day plus aspirin Clopidogrel 300 mg loading dose followed by 75 mg daily plus aspirin 21 days SOCRATES Ticagrelor 180 mg loading dose followed by 90 mg two times per day Aspirin 90 days CHANCE 2, Ticagrelor or Clopidogrel with Aspirin in High-Risk Patients with Acute Nondisabling Cerebrovascular Events II; PRINCE, Platelet Reactivity in Acute Stroke or Transient Ischaemic Attack; SOCRATES, Stroke or Transient Ischaemic Attack Treated with Aspirin or Ticagrelor and Patient Outcomes; THALES, Ticagrelor and ASA for Prevention of Stroke and Death.
