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The efficacy and safety of endovascular recanalization of occluded large cerebral arteries during the subacute phase of cerebral infarction: a case series report

Kangning Chen, Xianhua Hou, Zhenhua Zhou, Guangjian Li, Qu Liu, Li Gui, Jun Hu, Shugui Shi
DOI: 10.1136/svn-2017-000086 Published 22 September 2017
Kangning Chen
Department of Neurology, Southwest Hospital, Third Military Medical University, Chongqing, China
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Xianhua Hou
Department of Neurology, Southwest Hospital, Third Military Medical University, Chongqing, China
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Zhenhua Zhou
Department of Neurology, Southwest Hospital, Third Military Medical University, Chongqing, China
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Guangjian Li
Department of Neurology, Southwest Hospital, Third Military Medical University, Chongqing, China
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Qu Liu
Department of Neurology, Southwest Hospital, Third Military Medical University, Chongqing, China
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Li Gui
Department of Neurology, Southwest Hospital, Third Military Medical University, Chongqing, China
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Jun Hu
Department of Neurology, Southwest Hospital, Third Military Medical University, Chongqing, China
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Shugui Shi
Department of Neurology, Southwest Hospital, Third Military Medical University, Chongqing, China
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    Figure 1

    MR revealed a small infarct size and large area of low perfusion in the left hemisphere with the occlusion of left middle cerebral artery (MCA). (A) Diffusion-weighted MRI revealed an acute infarct in the left basal ganglia. (B) MR angiography showed that the M1 segment was occluded. (C) MRI re-examination after 8 days revealed an acute infarct in the left basal ganglia region with a small dot-like embolic infarct in the cortex. (D) There were large areas of low perfusion in the left MCA territory.

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    Figure 2

    The process of left middle cerebral artery (MCA) angioplasty.(A) A left MCA angioplasty. (B) The M1 segment of the left MCA was recanalized after angioplasty. (C) Digital subtraction angiography examination indicated that recanalization was successful after 40 days.

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    Figure 3

    MRI examination. (A) MRI revealed multiple clusters of ischaemic infarctions in bilateral cerebellar hemisphere. (B) Both vertebral arteries and basilar artery were occluded.

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    Figure 4

    Second MRI examination. On the ninth day of hospitalisation, MRI suggested worsening of bilateral cerebellar infarctions and the involvement of brainstem.

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    Figure 5

    Recanalization of the occluded basilar artery by percutaneous transluminal angioplasty and stenting. (A) Right ICA angiography revealed that the superior segment of the basilar artery and bilateral posterior cerebral arteries were partially supplied by posterior communicating artery. (B) Basilar artery was completely occluded in the middle segment and left posterior inferior cerebellar artery (PICA) showed compensatory enlargement. (C) Micro-catheter passed through the stenosis of the inferior segment of the basilar artery and revealed basilar artery occlusion beyond the middle segment. (D) After balloon dilation and implantation of the self-expandable stent, basilar artery was completely recanalized.

Tables

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  • Table 1

    Data of the 16 patients treated by percutaneous transluminal angioplasty or percutaneous transluminal angioplasty and stenting

    No.GenderAgeTime (onset to procedure) (days)Pre­operative NIHSSOccluded arterySympto
    matic
    Pre­operative TICI scorePost­operative TICI scoreComplica­tionPost­operative NIHSS (24 hours)Follow-up (months)90-Day mRS score
    1M56148LMCA M1Yes03None8640
    2M7297LMCA M1Yes13None7410
    3M35309LICA C6Yes03Central retinal artery embolism10351
    4F57617RMCA M1Yes02aNone7342
    5M59252RMCA M1Yes03None2330
    6M51237RMCA M1Yes03None7261
    7M25906LMCA M2Yes00None6240
    8M6348RMCA M1Yes03None8232
    9M45107RMCA M1Yes03None7230
    10M50486RMCA M1Yes03None6190
    11M51326RMCA M1Yes03None6172
    12F591412LMCA M1Yes13None12122
    13M552132BA and VA–V4Yes03None32113
    14F46286LMCA M1Yes02aNone690
    15M67208LMCA M1Yes00None832
    16M60649LMCA M1Yes03None931
    • BA, basilar artery; F, female; LICA, left internal carotid artery; LMCA, left middle cerebral artery; M, male; mRS, modified Rankin scale; NIHSS, National Institutes of Health Stroke Scale; RMCA,  right middle cerebral artery; TICI, thrombolysis in cerebral infarction; VA, vertebral artery.

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Vol 2 Issue 3 Table of Contents
Stroke and Vascular Neurology: 2 (3)
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The efficacy and safety of endovascular recanalization of occluded large cerebral arteries during the subacute phase of cerebral infarction: a case series report
Kangning Chen, Xianhua Hou, Zhenhua Zhou, Guangjian Li, Qu Liu, Li Gui, Jun Hu, Shugui Shi
Stroke and Vascular Neurology Sep 2017, 2 (3) 124-131; DOI: 10.1136/svn-2017-000086

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The efficacy and safety of endovascular recanalization of occluded large cerebral arteries during the subacute phase of cerebral infarction: a case series report
Kangning Chen, Xianhua Hou, Zhenhua Zhou, Guangjian Li, Qu Liu, Li Gui, Jun Hu, Shugui Shi
Stroke and Vascular Neurology Sep 2017, 2 (3) 124-131; DOI: 10.1136/svn-2017-000086
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The efficacy and safety of endovascular recanalization of occluded large cerebral arteries during the subacute phase of cerebral infarction: a case series report
Kangning Chen, Xianhua Hou, Zhenhua Zhou, Guangjian Li, Qu Liu, Li Gui, Jun Hu, Shugui Shi
Stroke and Vascular Neurology Sep 2017, 2 (3) 124-131; DOI: 10.1136/svn-2017-000086
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