Linear trend test of NIC for recanalisation and functional outcome
Median | Cases | No. of events | Univariable analysis | Multivariable analysis | |||
OR (95% CI) | P value | OR (95% CI) | P value | ||||
For successful recanalisation (AOL 2–3)† | |||||||
Tertiles | |||||||
Q1, low-level NIC (<0.126) | 0.108 | 36 | 14 (38.89 %) | 1.000 (Reference) | 1.000 (Reference) | ||
Q2, moderate-level NIC (0.126–0.163) | 0.142 | 36 | 25 (69.44%) | 3.571 (1.346, 9.475) | 0.011* | 2.936 (1.013, 8.511) | 0.047* |
Q3, high-level NIC (>0.163) | 0.200 | 36 | 31 (86.11%) | 9.743 (3.060, 31.020) | <0.001** | 12.433 (3.329, 46.427) | <0.001** |
P for trend | <0.001** | <0.001** | |||||
For good functional outcome (90-day mRS, 0–2)‡ | |||||||
Tertiles | |||||||
Q1, low-level NIC (<0.126) | 0.108 | 36 | 9 (25.00%) | 1.000 (Reference) | 1.000 (Reference) | ||
Q2, moderate-level NIC (0.126–0.163) | 0.142 | 36 | 19 (52.78%) | 3.353 (1.235, 9.102) | 0.018* | 5.209 (1.403, 19.339) | 0.014* |
Q3, high-level NIC (>0.163) | 0.200 | 36 | 25 (69.44%) | 6.818 (2.421, 19.201) | <0.001** | 16.382 (3.694, 72.655) | <0.001** |
P for trend | <0.001** | <0.001** |
P values in bold indicate statistical significance.
*p<0.05, **p<0.01.
†Adjusted for time from symptom onset to imaging and admission National Institutes of Health Stroke Scale (NIHSS) in multivariable analysis.
‡Adjusted for admission NIHSS and collateral score in multivariable analysis.
AOL, arterial occlusive lesion; mRS, modified Rankin Scale; NIC, normalised iodine concentration.