Multivariate logistic regression analysis for associations with aICAS
| Variables | Model1* | Model2† | Model3‡ | ||||
| OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | ||
| Metabolic syndrome | 1.70 (1.19~2.43) | 0.004 | 1.68 (1.17~2.41) | 0.005 | 1.68 (1.16~2.43) | 0.006 | |
| No. of MetS component | |||||||
| ≤1 | Ref. | Ref. | Ref. | ||||
| 2 | 1.49 (0.93~2.39) | 0.100 | 1.47 (0.91~2.36) | 0.114 | 1.48 (0.92~2.39) | 0.112 | |
| 3 | 2.01 (1.24~3.25) | 0.005 | 1.96 (1.21~3.18) | 0.006 | 1.97 (1.21~3.23) | 0.007 | |
| ≥4 | 2.10 (1.21~3.62) | 0.008 | 2.08 (1.20~3.59) | 0.009 | 2.10 (1.20~3.70) | 0.010 | |
| P value for trend | 0.001 | 0.002 | 0.002 | ||||
| Metsss, per SD increase | 1.36 (1.16~1.61) | ＜0.001 | 1.36 (1.16~1.61) | ＜0.001 | 1.36 (1.15~1.61) | ＜0.001 | |
| Quartiles of Metsss | |||||||
| Q1 (＜0.09) | Ref. | Ref. | Ref. | ||||
| Q2 (0.09–1.22) | 1.23 (0.67~2.28) | 0.507 | 1.24 (0.67~2.30) | 0.486 | 1.23 (0.66~2.28) | 0.513 | |
| Q3 (1.22–2.82) | 1.72 (0.96~3.08) | 0.066 | 1.72 (0.96~3.07) | 0.068 | 1.71 (0.95~3.07) | 0.073 | |
| Q4 (＞2.82) | 2.35 (1.34~4.12) | 0.003 | 2.37 (1.35~4.15) | 0.003 | 2.34 (1.32~4.13) | 0.004 | |
| P value for trend | ＜0.001 | ＜0.001 | ＜0.001 | ||||
*Model1: adjusted for sex and age.
†Model2: adjusted for Model1+ coronary artery heart disease.
‡Model3: adjusted for Model2+ hsCRP, MHR and NLR.
aICAS, asymptomatic intracranial arterial stenos; hsCRP, high-sensitivity C reactive protein; MetS, metabolic syndrome; Metsss, metabolic syndrome severity score; MHR, monocyte-to-high-density lipoprotein-cholesterol ratio; NLR, neutrophil-lymphocyte ratio.