Subgroup analyses of the outcome parameters
| Subgroup* | Endovascular therapy | Bridging therapy | RR (95% CI) | P value | P for interaction |
| Overall | 77 | 45 | |||
| Interval between stroke onset and arrival | 0.10 | ||||
| <4.5 hours | 14/54 (25.9) | 14/32 (43.8) | 1.69 (0.93 to 3.07) | 0.09 | |
| 4.5–6 hours | 7/23 (30.4) | 2/13 (15.4) | 0.51 (0.12 to 2.08) | 0.32 | |
| Stroke subtype | 0.16 | ||||
| Atherothrombotic | 6/20 (30.0) | 4/10 (40.0) | 1.33 (0.48 to 3.67) | 0.59 | |
| Cardioembolic | 10/44 (22.7) | 11/26 (42.3) | 1.86 (0.92 to 3.77) | 0.09 | |
| Undetermined or other | 5/13 (38.5) | 1/9 (11.1) | 0.29 (0.04 to 2.08) | 0.17 | |
| NIHSS score at admission | 0.75 | ||||
| <16 | 13/30 (43.3) | 9/18 (50.0) | 1.15 (0.62 to 2.14) | 0.66 | |
| ≥16 | 8/47 (17.0) | 7/27 (25.9) | 1.52 (0.62 to 3.74) | 0.36 | |
| Infarct core volume | 0.78 | ||||
| <70 mL | 15/43 (34.9) | 12/26 (46.2) | 1.32 (0.74 to 2.37) | 0.36 | |
| ≥70 mL | 6/34 (17.7) | 4/19 (21.1) | 1.19 (0.38 to 3.71) | 0.76 | |
*The outcome parameter of the subgroup analysis was the score of mRS ≤2.
mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale; RR, relative risk.