Association of clinical characteristics and unstable carotid plaque
| Characteristics | Total | IPN | P value | |
| IPN=0 (n=779) | IPN=1 (n=321) | |||
| Risk factors | ||||
| Age, year | 57.00 (49.00–63.00) | 57.00 (50.00–63.00) | 55.00 (49.00–63.00) | 0.3721 |
| Male, N (%) | 743 (67.55) | 494 (63.41) | 249 (77.57) | < 0.0001 |
| BMI, kg/㎡ | 25.02 (22.92–27.12) | 25.11 (22.86–27.14) | 24.93 (23.17–27.06) | 0.6327 |
| WHR | 0.89 (0.85–0.94) | 0.89 (0.84–0.94) | 0.91 (0.86–0.94) | 0.0073 |
| SBP, mm Hg | 128.00 (117.00–139.00) | 127.00 (117.00–138.00) | 130.00 (117.00–142.00) | 0.1029 |
| DBP, mm Hg | 78.00 (71.00–86.00) | 78.00 (71.00–86.00) | 78.00 (71.00–86.00) | 0.9920 |
| Smoking history, N (%) | 293 (26.64) | 181 (23.23) | 112 (34.89) | < 0.0001 |
| Hypertension, N (%) | 399 (36.27) | 271 (34.79) | 128 (39.88) | 0.1106 |
| Diabetes mellitus, N (%) | 230 (20.91) | 152 (19.51) | 78 (24.30) | 0.0759 |
| Dyslipidaemia, N (%) | 181 (16.45) | 136 (17.46) | 45 (14.02） | 0.1619 |
| Cardiovascular disease, N (%) | 68 (6.18) | 46 (5.91) | 22 (6.85) | 0.5526 |
| Baseline lipid parameters | ||||
| TC, mmol/L | 4.95 (4.27–5.55) | 4.90 (4.29–5.52) | 5.02 (4.23–5.60) | 0.5893 |
| TG, mmol/L | 1.31 (0.93–1.96) | 1.31 (0.92–1.96) | 1.32 (0.95–1.97) | 0.7515 |
| HDL-C, mmol/L | 1.42 (1.23–1.65) | 1.44 (1.24–1.66) | 1.39 (1.19–1.63) | 0.0473 |
| LDL-C, mmol/L | 3.00 (2.34–3.55) | 2.98 (2.34–3.51) | 3.05 (2.32–3.60) | 0.7016 |
| Non-HDL-C, mmol/L | 3.46 (2.79–4.07) | 3.42 (2.79–4.03) | 3.51 (2.80–4.12) | 0.2876 |
| RC, mmol/L | 0.42 (0.32–0.55) | 0.41 (0.30–0.55) | 0.45 (0.35–0.58) | 0.0010 |
| ApoA1, g/L | 1.49 (1.34–1.66) | 1.51 (1.36–1.68) | 1.43 (1.29–1.60) | < 0.0001 |
| ApoB, g/L | 0.90 (0.77–1.06) | 0.90 (0.77–1.05) | 0.91 (0.77–1.08) | 0.3249 |
| Others | ||||
| FBG, mmol/L | 5.24 (4.89–5.92) | 5.24 (4.88–5.85) | 5.27 (4.90–6.06) | 0.2561 |
| eGFR, mL/min | 109.42 (101.96–116.84) | 109.16 (102.10–116.70) | 110.44 (101.23–117.11) | 0.4753 |
ApoA1, apolipoprotein A1; ApoB, apolipoprotein B; BMI, body mass index; DBP, diastolic blood pressure; eGFR, estimated glomerular filtration rate; FBG, fasting blood glucose; HDL-C, high-density lipoprotein cholesterol; IPN, intraplaque neovascularisation; LDL-C, low-density lipoprotein cholesterol; RC, remnant cholesterol; SBP, systolic blood pressure; TC, total cholesterol; TG, triglycerides; WHR, waist-to-hip ratio.