Association between unstable carotid plaque and lipid parameters in the logistic regression analysis
| Lipid parameters | N (%） | OR (95% CI) P value | ||
| Crude model | Adjusted model 1 | Adjusted model 2 | ||
| RC, per 1 mmol/L increase | 321 (29.18%) | 1.437 (1036–1.994) 0.0299 | 1.364 (0.983–1.891) 0.0629 | 1.279 (0.905–1.807) 0.1633 |
| Quartiles of RC | ||||
| Q1 (< 0.32) | 56 (20.82%) | Ref. | Ref. | Ref. |
| Q2 (0.32-<0.42) | 74 (28.14%) | 1.489 (1.000–2.219) 0.0502 | 1.450 (0.969–2.169) 0.0706 | 1.377 (0.915–2.073) 0.1248 |
| Q3(0.42-<0.55) | 93 (34.19%) | 1.976 (1.343–2.909) 0.0006 | 1.934 (1.310–2.857) 0.0009 | 1.930 (1.292–2.882) 0.0013 |
| Q4(≥ 0.55) | 98 (33.11%) | 1.883 (1.286–2.756) 0.0011 | 1.774 (1.207–2.607) 0.0035 | 1.673 (1.113–2.515) 0.0134 |
| p value for trend | 0.0016 | 0.0048 | 0.0164 | |
| TC, per 1 mmol/L increase | 321 (29.18%) | 1.044 (0.920–1.185) 0.5005 | 1.111 (0.974–1.268) 0.1176 | 1.089 (0.945–1.256) 0.2377 |
| Quartiles of TC | ||||
| Q1 (< 4.265) | 83 (30.18%) | Ref. | Ref. | Ref. |
| Q2 (4.265-<4.95) | 66 (24.26%) | 0.741 (0.508–1.082) 0.1207 | 0.800 (0.544–1.177) 0.2572 | 0.823 (0.549–1.232) 0.3429 |
| Q3(4.95-<5.55) | 83 (30.63%) | 1.021 (0.709–1.471) 0.9099 | 1.121 (0.770–1.631) 0.5523 | 1.148 (0.774–1.704) 0.4928 |
| Q4(≥ 5.55) | 89 (31.56%) | 1.067 (0.744–1.528) 0.7248 | 1.246 (0.857–1.813) 0.2494 | 1.189 (0.796–1.775) 0.3978 |
| p value for trend | 0.4598 | 0.1261 | 0.2060 | |
| TG, per 1 mmol/L increase | 321 (29.18%) | 1.024 (0.92–1.129) 0.6340 | 1.003 (0.907–1.109) 0.9556 | 0.970 (0.869–1.084) 0.5956 |
| Quartiles of TG | ||||
| Q1 (< 0.93) | 73 (27.04%) | Ref. | Ref. | Ref. |
| Q2 (0.93-<1.31) | 85 (30.69%) | 1.195 (0.825–1.731) 0.3467 | 1.184 (0.814–1.722) 0.3770 | 1.112 (0.757–1.632) 0.5883 |
| Q3(1.31-<1.96) | 81 (29.35%) | 1.121 (0.772–1.628) 0.5487 | 1.087 (0.745–1.585) 0.6647 | 1.008 (0.680–1.495) 0.9664 |
| Q4(≥ 1.96) | 82 (29.60%) | 1.135 (0.782–1.647) 0.5057 | 1.062 (0.727–1.551) 0.7557 | 0.948 (0.625–1.438) 0.8031 |
| p value for trend | 0.6889 | 0.9836 | 0.6239 | |
| HDL-C, per 1 mmol/L increase | 321 (29.18%) | 0.708 (0.467–1.073) 0.1033 | 1.042 (0.662–1.640) 0.8598 | 1.065 (0.652–1.742) 0.8006 |
| Quartiles of HDL-C | ||||
| Q1 (< 1.23) | 90 (33.33%) | Ref. | Ref. | Ref. |
| Q2 (1.23-<1.42) | 81 (30.80%) | 0.890 (0.618–1.281) 0.5308 | 0.916 (0.635–1.321) 0.6376 | 0.948 (0.653–1.376) 0.7785 |
| Q3(1.42-<1.65) | 71 (25.18%) | 0.673 (0.465–0.974) 0.0355 | 0.766 (0.526–1.116) 0.1649 | 0.778 (0.527–1.148) 0.2058 |
| Q4(≥ 1.65) | 79 (27.72%) | 0.767 (0.534–1.102) 0.1513 | 1.037 (0.703–1.530) 0.8545 | 1.030 (0.682–1.557) 0.8874 |
| p value for trend | 0.0949 | 0.9934 | 0.9614 | |
| LDL-C, per 1 mmol/L increase | 321 (29.18%) | 1.024 (0.886–1.185) 0.7445 | 1.066 (0.917–1.239) 0.4086 | 1.050 (0.893–1.235) 0.5528 |
| Quartiles of LDL-C | 1.024 (0.886–1.185)0.7445 | 1.066 (0.917–1.239) 0.4086 | 1.050 (0.893–1.235) 0.5528 | |
| Q1 (<2.34) | 82 (30.04%) | Ref. | Ref. | Ref. |
| Q2 (2.34≤3.00) | 72 (26.09%) | 0.822 (0.566–1.194) 0.3033 | 0.861 (0.589–1.259) 0.4407 | 0.872 (0.585–1.301) 0.5033 |
| Q3(3.00≤3.55) | 80 (28.99%) | 0.951 (0.659–1.372) 0.7872 | 0.973 (0.668–1.418) 0.8878 | 0.948 (0.635–1.415) 0.7945 |
| Q4(≥ 3.55) | 87 (31.64%) | 1.078 (0.750–1.549) 0.6852 | 1.170 (0.804–1.701) 0.4124 | 1.121 (0.750–1.674) 0.5785 |
| p value for trend | 0.5560 | 0.3350 | 0.4813 | |
| Non-HDL-C, per 1 mmol/L increase | 321 (29.18%) | 1.089 (0.953–1.245) 0.2104 | 1.119 (0.974–1.286) 0.1112 | 1.094 (0.941–1.270) 0.2423 |
| Quartiles of Non-HDL-C | ||||
| Q1 (<2.79) | 78 (28.78%) | Ref. | Ref. | Ref. |
| Q2 (2.79≤3.46) | 73 (26.55%) | 0.894 (0.614–1.301) 0.5591 | 0.911 (0.623–1.334) 0.6334 | 0.895 (0.601–1.332) 0.5834 |
| Q3(3.46≤4.07) | 79 (28.42%) | 0.982 (0.678–1.422) 0.9246 | 1.015 (0.693–1.487) 0.9375 | 0.978 (0.656–1.458) 0.9136 |
| Q4(≥4.07) | 91 (32.97%) | 1.217 (0.846–1.751) 0.2894 | 1.296 (0.891–1.886) 0.1755 | 1.229 (0.822–1.837) 0.3151 |
| p value for trend | 0.2519 | 0.1454 | 0.2593 | |
| ApoA1, per 1 g/L increase | 321 (29.18%) | 0.277 (0.157–0.490) <0.0001 | 0.397 (0.215–0.735) 0.0033 | 0.350 (0.185–0.664) 0.0013 |
| Quartiles of ApoA1 | ||||
| Q1 (＜1.34） | 105 (39.03%) | Ref. | Ref. | Ref. |
| Q2 (1.34≤1.49） | 78 (29.43%) | 0.651 (0.454–0.934) 0.0197 | 0.683 (0.475–0.981) 0.0393 | 0.648 (0.448–0.938) 0.0213 |
| Q3 (1.49≤1.66） | 73 (25.98%) | 0.548 (0.382–0.787) 0.0011 | 0.610 (0.422–0.882) 0.0085 | 0.576 (0.395–0.841) 0.0042 |
| Q4 (≥1.66） | 65 (22.81%) | 0.461 (0.319–0.668) <0.0001 | 0.593 (0.398–0.882) 0.0100 | 0.549 (0.364–0.830) 0.0045 |
| p value for trend | <0.0001 | 0.0087 | 0.0041 | |
| ApoB, per 1 g/L increase | 32129.18%） | 1.332 (0.748–2.371) 0.3302 | 1.414 (0.781–2.561) 0.2529 | 1.256 (0.658–2.396) 0.4898 |
| Quartiles of ApoB | ||||
| Q1 (＜0.77） | 80 (29.41%) | Ref. | Ref. | Ref. |
| Q2 (0.77≤0.90） | 71 (26.49%) | 0.865 (0.594–1.260) 0.4500 | 0.868 (0.593–1.272) 0.4691 | 0.871 (0.586–1.295) 0.4960 |
| Q3 (0.90≤1.06） | 80 (28.07%) | 0.937 (0.649–1.352) 0.7265 | 0.948 (0.651–1.381) 0.7808 | 0.925 (0.623–1.373) 0.6982 |
| Q4 (≥1.06） | 90 (32.73%) | 1.168 (0.812–1.678) 0.4023 | 1.194 (0.823–1.731) 0.3505 | 1.125 (0.754–1.677) 0.5642 |
| p value for trend | 0.3452 | 0.2897 | 0.4841 | |
Crude model: unadjusted. Model 1: adjusted for sex and age. Model 2: adjusted for sex, age, BMI, WHR, SBP, DBP, FBG, eGFR, smoking history, hypertension, dyslipidaemia, diabetes mellitus, and cardiovascular disease.
ApoA1, apolipoprotein A1; ApoB, apolipoprotein B; BMI, body mass index; DBP, diastolic blood pressure; eGFR, estimated glomerular filtration rate; FBG, fasting blood glucose; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; RC, remnant cholesterol; SBP, systolic blood pressure; TC, total cholesterol; TG, triglycerides; WHR, waist-to-hip ratio.