Differences in MMSE scores and cognitive domain scores in patients before and after treatment with butylphthalide
Butylphthalide (n=309) | Control (n=296) | P value | |
MMSE | |||
D-value, mean (SD) | 0.21 (2.91) | 1.13 (3.93) | 0.001 |
D-value percentage, mean (SD) | 0.01 (0.12) | 0.04 (0.17) | 0.002 |
Cognitive domain D-value | |||
Orientation, mean (SD) | 0.02 (1.56) | 0.40 (2.07) | 0.010 |
Registration, mean (SD) | 0.03 (0.42) | 0.10 (0.67) | 0.121 |
Attention and calculation, mean (SD) | 0.13 (1.51) | 0.27 (1.67) | 0.256 |
Recall, mean (SD) | −0.003 (1.09) | 0.04 (1.12) | 0.599 |
Language, mean (SD) | 0.04 (1.13) | 0.31 (1.32) | 0.008 |
Cognitive domain D-value percentage | |||
Orientation, mean (SD) | −0.01 (0.20) | 0.03 (0.25) | 0.018 |
Language, mean (SD) | −0.004 (0.16) | 0.03 (0.19) | 0.015 |
MMSE, mini-mental state examination.