Sensitivity and specificity of combination of ABCD2, truncal ataxia and HINTS in the differentiation of PCS with VN
Variables | Sensitivity, % (95% CI) | Specificity, % (95% CI) | Positive predictive value, % (95% CI) | Negative predictive value, % (95% CI) |
HINTS plus ABCD2≥3 | 98.1 (88.4% to 99.9%) | 52.2 (39.9% to 64.2%) | 60.7 (49.4% to 71.0%) | 97.3 (84.2% to 99.9%) |
HINTS plus ABCD2≥4 | 96.2 (85.7% to 99.3%) | 76.6 (61.6% to 87.2%) | 82.0 (69.6% to 90.2%) | 94.7 (80.9% to 99.1%) |
HINTS plus truncal ataxia (3) | 98.1 (88.4% to 99.9%) | 100.0 (93.4% to 100.0%) | 100.0 (91.3% to 100.0%) | 98.6 (91.2% to 99.9%) |
HINTS plus truncal ataxia (2 and 3) | 100.0 (91.4% to 100.0%) | 94.2 (85.1% to 98.1%) | 92.9 (81.9% to 97.7%) | 100.0 (93.0% to 100.0%) |
ABCD2≥4 plus truncal ataxia (2 and 3) | 94.2 (83.1% to 98.5%) | 81.2 (69.6% to 89.2%) | 79.0 (66.5% to 87.9%) | 94.9 (84.9% to 98.7%) |
HINTS, head impulse-nystagmus-test of skew; PCS, posterior circulation stroke; VN, vestibular neuritis.