Trials with clinical and imaging outcomes: comparing numbers screened, randomised, centres, recruitment rates, completeness of follow-up
| PROGRESS | VITATOPS | SPRINT/SPRINT MIND | PROSPER | PROFESS | ACCORD/ACCORD MIND | LACI-1 | ||||||||
| Clinical | Imaging | Clinical | Imaging | Clinical | Imaging | Clinical | Imaging | Clinical | Imaging | Clinical | Imaging | Clinical | Imaging | |
| Screened | 7121 | 323 | N/A | N/A | 14 692 | 1267 | 23 770 | 1100 | N/A | N/A | 19 716 | N/A | N/A | N/A |
| Randomised | 6105 | 254 | 8164 | 471 | 9361 | 673 | 5804 | 646 | 20 333 | 1057 | 10 251 | 632 | 57 | 27 |
| Follow-up complete | 6102 (99.9%) | 192 (75.6%) | 7462 (91.4%) | 359 (76.2%) | 8563 (91.5%) | 454 (67.5%) | 5147 (88.7%) | 554 (85.8%) | 20 208 (99.4%) | 771 (72.9%) | 10 201 (99.5%) | 503 (79.6%) | 56 (98.3%) | 22 (81.5%) |
| Centres | 172 | 10 | 123 | 5 | 101 | 7 | 3 | 1 | 695 | ? | 77 | 28 | 2 | 1 |
| Recruitment rate | 1.18 | 0.85 | 0.55 | 3.77 | 3.31 | 3.43 | 113.8 | 38 | 0.86 | ? | 3.69 | 0.81 | 1.67 | 1.59 |
| Follow-up duration | 46.8 | 36 | 40.8 | 25 | 39.1 | 6.5 | 38.4 | 33 | 30 | 27.9 | 42 | 35 | 3 | 3 |
| Age (mean) | 64 | 60.8 | 62.6 | 64.3 | 67.9 | 67.3 | 75.4 | 75 | 66.2 | 65.4 | 62.2 | 62.4 | 66.1 | 68 |