Propensity score matching analysis for primary outcome
| Primary outcome | Subgroup | Clopidogrel plus aspirin | Aspirin alone | RD (95% CI)* | P value | Pint value |
| END at 7 days† | SBP<140 mm Hg (N=940) | 17/490 (3.5) | 19/450 (4.2) | −0.8 (−3.2 to 1.7) | 0.55 | 0.91 |
| SBP≥140 mm Hg (N=940) | 27/494 (5.5) | 31/446 (7.0) | −1.5 (−4.6 to 1.6) | 0.35 |
*Calculated using the generalised liner model.
†END was defined as an increase between baseline and 7 days of ≥2 on the NIHSS score, but not as result of cerebral haemorrhage.18
END, early neurological deterioration; NIHSS, National Institutes of Health Stroke Scale; RD, risk difference; SBP, systolic blood pressure.