Association of APOE with ICH locations
| Non-lobar ICH (n=395) | Lobar ICH (n=138) | Univariate | Multivariate (age adjusted) | |||
| OR (95% CI) | P value | OR (95% CI) | P value | |||
| APOE, N (%) | ||||||
| APOE ε2 dominant | ||||||
| Any allele | 61 (15.4) | 28 (20.3) | 1.394 (0.848 to 2.290) | 0.190 | 1.438 (0.855 to 2.417) | 0.171 |
| APOE ε2 additive | ||||||
| 1 allele | 59 (14.9) | 26 (18.8) | 1.338 (0.804 to 2.226) | 0.306 | 1.384 (0.813 to 2.356) | 0.303 |
| 2 alleles | 2 (0.5) | 2 (1.4) | 3.036 (0.423 to 21.811) | 3.062 (0.364 to 25.726) | ||
| APOE ε4 dominant | ||||||
| Any allele | 57 (14.4) | 32 (23.2) | 1.790 (1.102 to 2.907) | 0.019 | 1.894 (1.138 to 3.154) | 0.014 |
| APOE ε4 additive | ||||||
| 1 allele | 55 (13.9) | 26 (18.8) | 1.507 (0.901 to 2.523) | 0.009 | 1.551 (0.903 to 2.664) | 0.004 |
| 2 alleles | 2 (0.5) | 6 (4.3) | 9.566 (1.902 to 48.102) | 14.368 (2.557 to 80.717) | ||
| APOE ε2/ε4 | 3 (0.8) | 6 (4.3) | 5.939 (1.465 to 24.082) | 0.013 | 6.098 (1.414 to 26.293) | 0.015 |
ICH, intracerebral haemorrhage; APOE, apolipoprotein E.