Table 1

Assessment flow chart

	Screening		Follow-up
	Baseline	Randomisation	Immediately postoperative	24±6 hours	48±12 hours	72±12 hours	7 days±12 hour or at discharge	90±7 days
Inclusion/exclusion criteria	x
Informed consent	x
Randomisation		x
Demographics	x
Medical history	x
Previous medication	x
Vital signs	x		x	x	x	X	x
Physical examination	x
Laboratory tests	x			x	x	X	x
Prestroke mRS	x
mRS								x
NIHSS score	x			x		X	x
Brain CT plus CTP/MRI	x
CTA/MRA/DSA	x					X
Brain CT/MRI						X
ASPECTS	x
mTICI score			x
AOL grade						X
Comedication			x	x	x	X	x	x
Barthel index								x
EQ-5D								x
AE/SAE			x	x	x	X	x	x

AE, adverse event; ASPECTS, Alberta Stroke Programme Early CT Score; CTA, CT angiography; CTP, CT perfusion; DSA, digital subtraction angiography; EQ-5D, EuroQol 5 Dimensions Questionnaire; AOL grade, American Society of Interventional and Therapeutic Neuroradiology (ASITN)-Society of Interventional Radiology (SIR) Grading System for Thrombolysis in Acute Ischaemic Stroke; MRA, MR angiography; mRS, modified Rankin scale; mTICI, modified Thrombolysis in Cerebral Infarction; NIHSS, National Institute of Health Stroke Scale; SAE, serious adverse event; TOAST, Trial of Org 10 172 in Acute Stroke Treatment classification.