Inverse-probability weighting (IPW) analysis to show the effect of IVT, NWU and ASPECTS on sICH
| sICH | ATE | 95% CI | P value |
| IVT (unadjusted) | +12.4% | −0.14 to 26.3 | 0.08 |
| IVT (adjusted*) | +16.8% | 5.3 to 28.4 | <0.01 |
| Low ASPECTS (median) | +9.8% | −0.05 to 24.3 | 0.03 |
| High NWU (median) | +17.5% | 4.9 to 30.1 | <0.01 |
| IVT in high NWU | +36.1% | 11.2 to 61.0 | <0.01 |
| IVT in low ASPECTS | +48.2% | 23.8 to 72.5 | <0.001 |
| IVT in high ASPECTS | +4.9% | −0.05 to 15.0 | 0.34 |
| IVT in low NWU | +3.4% | −0.03 to 9.97 | 0.30 |
*Adjusted for age, NIHSS, NWU, ASPECTS and recanalisation status.
ASPECTS, Alberta Stroke Program Early CT Score; ATE, average treatment effect; IVT, intravenous thrombolysis with alteplase; NIHSS, National Institute of Health Stroke Scale; NWU, net water uptake; sICH, symptomatic intracerebral haemorrhage.