Complications and outcomes in stented patients in relation to aspirin and thrombolysis
| Aspirin given intraoperatively (n=49) | No aspirin given intraoperatively (n=53) | |||||
| Thrombolysed (n=34) | Not thrombolysed (n=15) | P value | Thrombolysed (n=42) | Not thrombolysed (n=11) | P value | |
| Thrombolysis in cerebral infarct score ≥2b (n (%)) | 33 (97%) | 10 (67%) | 0.008* | 39 (93%) | 10 (90%) | 1* |
| NIHSS at 7 days median (IQR) | 5 (2–14) | 16 (2–36) | 0.09† | 15 (3–34) | 15(5–21) | 0.63† |
| NIHSS difference baseline to 7 days median (IQR) | 12 (4–18) | 7 (-7–10) | 0.01† | 4 (-6–9) | 2 (–12–4) | 0.24† |
| Infarction at 24 hours (n (%)) | 26 (76%) | 9 (60%) | 0.31* | 34 (81%) | 10 (91%) | 0.67* |
| Malignant middle cerebral artery syndrome (n (%)) | 0 (0%) | 1 (7%) | 0.31* | 5 (12%) | 0 (0%) | 0.57* |
| Hemicraniectomy (n (%)) | 0 (0%) | 1 (7%) | 0.31* | 1 (2%) | 0 (0%) | 1* |
| Symptomatic intracerebral haemorrhage (n (%)) | 1 (3%) | 1 (6%) | 1* | 4 (10%) | 5 (46%) | 0.01* |
| Subarachnoid haemorrhage (n (%)) | 4 (12%) | 2 (13%) | 1* | 2 (5%) | 2 (18%) | 0.19* |
| Stroke within 90 days (n (%)) | 0 (0%) | 0 (0%) | 1* | 0 (0%) | 0 (0%) | 1* |
| Death at 90 days (n (%)) | 4 (12%) | 6 (40%) | 0.05* | 8 (19%) | 4 (36%) | 0.24* |
| mRS 0–2 at 90 days (n (%)) | 20 (59%) | 5 (33%) | 0.18‡ | 16 (38%) | 3 (27%) | 0.73* |
*Fisher’s exact test.
†Mann-Whitney U test.
‡Z-test.
mRS, modified Rankin Scale; NIHSS, National Institutes for Health Stroke Scale score.