Characteristics of patients with hospital-based unruptured intracranial aneurysm (UIA) who underwent microsurgical clipping or endovascular treatment
Microsurgical clipping | Endovascular treatment | ||||
Total (N=1176) | Total (N=1393) | Patients with RAO (N=11) | P value | ||
Age (years) | 60.6±9.1 | 59.5±10.9 | 51.3±7.9 | 0.011 | |
<40 | 32 (2.7%) | 72 (5.2%) | 1 (9.1%) | ||
40–64 | 733 (53.5%) | 830 (59.6%) | 10 (90.9%) | ||
65–74 | 368 (31.3%) | 396 (28.4%) | 0 | ||
≥75 | 43 (3.7%) | 95 (6.8%) | 0 | ||
Female | 859 (73.0%) | 1075 (77.2%) | 9 (81.8%) | >0.999 | |
Comorbidities | |||||
Hypertension | 619 (52.6%) | 669 (48.0%) | 5 (45.5%) | 0.864 | |
Diabetes mellitus | 152 (13.4%) | 162 (11.7%) | 1 (9.1%) | >0.999 | |
Dyslipidaemia | 416 (35.4%) | 502 (36.0%) | 3 (27.3%) | 0.755 | |
Chronic kidney disease | 20 (1.7%) | 33 (2.4%) | 0 | >0.999 | |
Multiplicity | 522 (38.1%) | 599 (39.2%) | 5 (45.5%) | 0.760 | |
Size of UIA (mm) | 4.62 | 6.21±3.54 | 5.70±1.67 | 0.335 | |
<5 | 935 (68.3%) | 652 (42.7%) | 3 (27.3%) | ||
5–10 | 402 (29.4%) | 732 (47.9%) | 8 (72.7%) | ||
10–15 | 24 (1.8%) | 89 (5.8%) | 0 | ||
≥15 | 8 (0.6%) | 54 (3.5%) | 0 | ||
Direction of UIA | 0.197 | ||||
Central | 225 (16.4%) | 312 (20.4%) | 0 | ||
Left | 614 (44.9%) | 655 (42.9%) | 5 (45.5%) | ||
Right | 530 (38.7%) | 560 (36.7%) | 6 (54.5%) | ||
Location of UIA | 0.063 | ||||
Internal carotid artery* | 319 (23.3%) | 921 (60.3%) | 11 (100%) | ||
Anterior cerebral artery | 293 (21.4%) | 302 (19.8%) | 0 | ||
Middle cerebral artery | 749 (54.7%) | 129 (8.4%) | 0 | ||
Posterior circulation | 8 (0.6%) | 175 (11.5%) | 0 | ||
Associated vascular problems | |||||
Atherosclerosis/stenosis | 62 (4.5%) | 226 (14.8%) | 1 (9.1%) | >0.999 | |
Diffusion restriction | NA | 262 (17.2%) | 2 (18.2%) | >0.999 | |
Intraoperative carotid artery dissection | NA | 7 (0.5%) | 0 | >0.999 | |
Intraoperative thrombosis | NA | 79 (4.8%) | 0 | >0.999 | |
Device | |||||
Simple coil embolisation | NA | 427 (28.0%) | 1 (9.1%) | 0.307 | |
Balloon microcatheter | NA | 92 (5.0%) | 3 (27.3%) | 0.016 | |
Stent assisted | NA | 792 (50.9%) | 3 (27.3%) | 0.310 | |
Flow diverter | NA | 174 (11.4%) | 4 (36.4%) | 0.132 | |
Flow disruptor | NA | 57 (3.7%) | 0 | >0.999 | |
Post-operative antiplatelet | |||||
None | NA | 315 (20.6%) | 2 (18.1%) | 0.923 | |
Single | NA | 184 (12.0%) | 1 (9.1%) | ||
Dual+@ | NA | 1028 (67.3%) | 8 (72.8%) | ||
Retreatment | 57 (4.2%) | 97 (6.4%) | 0 | >0.999 |
*Ten cases of RAO occurred in paraclinoid aneurysm (1.6%, from a total of 622 patients) and one case of RAO occurred in distal paraclinoid aneurysm (0.4%, from a total of 255 patients).
NA, not applicable; RAO, retinal artery occlusion.