Baseline characteristics of EVT with and without CAS patients
| Characteristics | EVT with CAS (n=169) | EVT without CAS (n=264) | P value |
| Age - years | 70 (63–77) | 72 (64–79) | 0.04 |
| Male | 120/169 (71) | 166/264 (63) | 0.08 |
| Medical history | |||
| Atrial fibrillation | 11/168 (6.5) | 45/261 (17.2) | <0.01 |
| Diabetes mellitus | 22/167 (13.2) | 40/260 (15.4) | 0.53 |
| Hypercholesterolaemia | 64/167 (38.3) | 71/249 (28.5) | 0.04 |
| Hypertension | 83/166 (50.0) | 139/259 (53.7) | 0.46 |
| Myocardial infarction | 12/166 (7.2) | 44/260 (16.9) | <0.01 |
| Peripheral artery disease | 25/167 (15.0) | 32/261 (12.3) | 0.42 |
| Previous stroke | 20/168 (11.9) | 38/261 (14.6) | 0.43 |
| Current smoker | 65/140 (46.4) | 69/190 (36.3) | 0.06 |
| Current medication use | |||
| Antiplatelet | 44/166 (26.5) | 81/260 (31.2) | 0.30 |
| DOAC | 2/168 (1.2) | 4/259 (1.5) | >0.99 |
| Coumarin | 8/168 (4.8) | 34/262 (13.0) | 0.01 |
| Heparin | 0/167 (0) | 6/259 (2.3) | 0.09 |
| Antihypertensive medication | 81/166 (48.8) | 145/256 (56.6) | 0.11 |
| Statin | 58/165 (35.2) | 94/258 (36.4) | 0.79 |
| Pre-stroke mRS score >0 | 28/165 (17.0) | 56/255 (22.0) | 0.21 |
| Left hemisphere | 86/169 (50.9) | 145/264 (54.9) | 0.41 |
| Ipsilateral extracranial ICA lesion | |||
| Carotid stenosis 50–99% | 68/169 (40.2) | 130/264 (49.2) | 0.07 |
| Carotid occlusion | 101/169 (59.8) | 134/264 (50.8) | 0.07 |
| NIHSS score | 16 (11–19) | 16 (12–19) | 0.68 |
| ASPECTS | 8 (7–10) | 9 (7–10) | 0.87 |
| Collateral filling | <0.01 | ||
| Absent collaterals | 3/161 (1.9) | 22/255 (8.6) | |
| <50% of occluded territory | 48/161 (29.8) | 99/255 (38.8) | |
| 50–99% of occluded territory | 73/161 (45.3) | 94/255 (36.9) | |
| 100% of occluded territory | 37/161 (23.0) | 40/255 (15.7) | |
| Intravenous thrombolysis | 150/168 (89.3) | 214/262 (81.7) | 0.03 |
| Pre-intervention DBP - mm Hg | 82±16 | 83±15 | 0.92 |
| Pre-intervention SBP - mm Hg | 154±26 | 154±23 | >0.99 |
Data are presented as n (%), mean±SD or median (IQR). The data in this table are based on the data set before imputation. For some variables, the denominators are smaller than the number of patients included due to missing data.
ASPECTS, Alberta Stroke Programme Early CT Score; CAS, carotid artery stenting; DBP, diastolic blood pressure; DOAC, direct oral anticoagulants; EVT, endovascular treatment; ICA, internal carotid artery; mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke; SBP, systolic blood pressure.