Comparison of various published clinical scales with RF model to predict LVO in the test set
Cut-off | AUC (95% CI) | SEN | SPE | Accuracy | |
RF | — | 0.831 (0.819 to 0.843) | 0.721 | 0.827 | 0.772 |
mNIHSS | ≥7 | 0.809 (0.795 to 0.824) | 0.760 | 0.755 | 0.769 |
sNIHSS-EMS | ≥6 | 0.809 (0.795 to 0.824) | 0.722 | 0.788 | 0.764 |
NIHSS | ≥6 | 0.806 (0.792 to 0.820) | 0.727 | 0.792 | 0.708 |
RACE | ≥5 | 0.806 (0.791 to 0.821) | 0.712 | 0.793 | 0.764 |
CPSSS | ≥2 | 0.804 (0.789 to 0.819) | 0.658 | 0.826 | 0.761 |
FAST-ED | ≥4 | 0.804 (0.790 to 0.819) | 0.611 | 0.850 | 0.760 |
s-NIHSS-5 | ≥4 | 0.804 (0.790 to 0.819) | 0.738 | 0.763 | 0.760 |
3I-SS | ≥4 | 0.798 (0.782 to 0.813) | 0.641 | 0.852 | 0.759 |
LAMS | ≥4 | 0.779 (0.764 to 0.795) | 0.652 | 0.808 | 0.746 |
PASS | ≥2 | 0.778 (0.763 to 0.794) | 0.660 | 0.823 | 0.751 |
s-NIHSS-1 | ≥2 | 0.773 (0.757 to 0.789) | 0.698 | 0.761 | 0.695 |
FPSS | ≥5 | 0.762 (0.746 to 0.778) | 0.781 | 0.620 | 0.711 |
G-FAST | ≥3 | 0.755 (0.740 to 0.771) | 0.763 | 0.653 | 0.697 |
VAN | ≥2 | 0.732 (0.715 to 0.748) | 0.847 | 0.534 | 0.650 |
ROSIER | ≥4 | 0.730 (0.714 to 0.746) | 0.886 | 0.467 | 0.694 |
FAST | ≥3 | 0.706 (0.690 to 0.723) | 0.682 | 0.681 | 0.685 |
aNIHSS | ≥1 | 0.689 (0.672 to 0.706) | 0.542 | 0.751 | 0.416 |
aNIHSS, abbreviated NIHSS; AUC, area under the curve; CPSSS, Cincinnati Pre-hospital Stroke Severity scale; EMS, emergency medical services; FAST-ED, Field Assessment Stroke Triage for Emergency Destination scale; FPSS, Finnish Prehospital Stroke Scale; G-FAST, gaze–face–arm–speech–time test; 3I-SS, three-item Stroke Scale; LAMS, Los Angeles Motor Scale; LVO, large vessel occlusion stroke; mNIHSS, modified NIHSS; NIHSS, National Institutes of Health Stroke Scale; PASS, Pre-hospital Acute Stroke Severity scale; RACE, Rapid Arterial Occlusion Evaluation Scale; RF, random forests; ROSIER, Recognition of Stroke in the Emergency Room; SEN, sensitivity; sNIHSS, shortened versions of the NIHSS; SPE, specificity; VAN, stroke vision, aphasia, neglect assessment.