Association between BPV and stroke recurrence in patients who had IS, stratified by TOAST subtypes
| Time | BP SD (mm Hg) | Stroke subtypes | Unadjusted HR (95% CI) | Unadjusted P value | Adjusted HR (95% CI) | Adjusted P value |
| 24 hours | SBP SD ≥12.5 | All | 2.50 (1.07 to 5.84) | 0.03 | 1.88 (0.78 to 4.55) | 0.16 |
| LAA | 2.65 (0.93 to 7.50) | 0.07 | 2.27 (0.76 to 6.78) | 0.14 | ||
| SAO | 2.29 (0.53 to 9.99) | 0.27 | 1.51 (0.32 to 7.12) | 0.60 | ||
| DBP SD ≥14.0 | All | 1.65 (0.892 to 2.96) | 0.10 | 1.41 (0.74 to 2.68) | 0.30 | |
| LAA | 1.48 (0.69 to 3.17) | 0.31 | 1.04 (0.45 to 2.42) | 0.93 | ||
| SAO | 2.08 (0.81 to 5.37) | 0.13 | 2.05 (0.70 to 6.03) | 0.19 | ||
| Night-time | SBP SD ≥14.5 | All | 1.64 (0.95 to 2.83) | 0.07 | 1.37 (0.78 to 2.42) | 0.27 |
| LAA | 1.28 (0.63 to 2.57) | 0.50 | 1.08 (0.52 to 2.26) | 0.84 | ||
| SAO | 2.77 (1.07 to 7.15) | 0.04 | 1.95 (0.70 to 5.44) | 0.20 | ||
| DBP SD ≥11.5 | All | 1.85 (1.07 to 3.21) | 0.03 | 1.70 (0.95 to 3.05) | 0.07 | |
| LAA | 1.33 (0.64 to 2.77) | 0.45 | 1.04 (0.48 to 2.25) | 0.93 | ||
| SAO | 3.60 (1.39 to 9.29) | 0.008 | 3.87 (1.40 to 10.71) | 0.01 | ||
| Daytime | SBP SD ≥16.5 | All | 1.67 (0.97 to 2.87) | 0.06 | 1.53 (0.87 to 2.70) | 0.14 |
| LAA | 1.72 (0.88 to 3.34) | 0.11 | 1.66 (0.83 to 3.32) | 0.15 | ||
| SAO | 1.56 (0.61 to 3.96) | 0.35 | 0.98 (0.33 to 2.84) | 0.96 | ||
| DBP SD ≥7.5 | All | 2.75 (0.86 to 8.83) | 0.09 | 2.50 (0.76 to 8.23) | 0.13 | |
| LAA | 3.02 (0.72 to 12.58) | 0.13 | 3.03 (0.70 to 13.20) | 0.14 | ||
| SAO | 2.54 (0.34 to 19.15) | 0.37 | 2.26 (0.29 to 17.80) | 0.44 |
P values are related to the comparison of patients with and without HBPV.
BP, blood pressure; BPV, blood pressure variability; DBP, diastolic blood pressure; HBPV, high blood pressure variability; IS, ischaemic stroke; LAA, large artery atherosclerosis; SAO, small artery occlusion; SBP, systolic blood pressure; TOAST, Trial of Org 10172 in Acute Stroke Treatment.