Baseline characteristics and outcomes of 26 hospitals included in all three cohorts
| CNSR-I 2007–2008 (n=3015) | CNSR-II 2012–2013 (n=1984) | CNSR-III 2015–2018 (n=1750) | P for trend* | |
| Demographics | ||||
| Age, median (IQR), y | 65 (55–73) | 64 (55–73) | 62 (54–69) | 0.990 |
| Ethnicity (non-Han) | 149 (4.94) | 99 (4.99) | 53 (3.03) | 0.004 |
| Female sex | 1080 (35.8) | 687 (34.6) | 504 (28.8) | <0.001 |
| In-hospital outcomes | ||||
| mRS ≤2 at discharge | 2164 (71.9) | 1533 (77.3) | 1247 (71.3) | 0.745 |
| In-hospital mortality | 68 (2.3) | 22 (1.1) | 2 (0.1) | <0.001 |
| 1 year outcomes | ||||
| MI or vascular death | 348 (11.5) | 129 (6.50) | 15 (0.9) | <0.001 |
| MI or non-stroke vascular death | 100 (3.3) | 54 (2.72) | 8 (0.5) | <0.001 |
| MI or all-cause death | 409 (13.6) | 158 (8.0) | 45 (2.6) | <0.001 |
| Recurrent stroke | 544 (18.0) | 132 (6.7) | 171 (9.8) | <0.001 |
| Vascular death | 307 (10.2) | 95 (4.8) | 11 (0.6) | <0.001 |
| MI | 50 (1.7) | 35 (1.8) | 5 (0.3) | <0.001 |
Values are presented as n (%) unless otherwise indicated.
*Based on ANOVA.
CNSR, China National Stroke Registry; MI, myocardial infarction; mRS, modified Rankin scale.