Baseline characteristics of participants
All | Clopidogrel only | Aspirin+clopidogrel | P value | |
n (%) | 62 (100.0) | 59 (95.2) | 3 (4.8) | |
Male (%) | 33 (53.2) | 33 (55.9) | 0 | 0.058 |
Age, years | 63.7 (13.7) | 63.0 (13.5) | 78.0 (8.9) | 0.06 |
Preindex event | ||||
Stroke (%) | 9 (14.5) | 8 (13.6) | 1 (33.3) | 0.34 |
TIA (%) | 8 (12.9) | 6 (10.2) | 2 (66.7) | 0.004 |
IHD (%) | 6 (9.7) | 5 (8.5) | 1 (33.3) | 0.16 |
Diabetes (%) | 11 (17.7) | 10 (16.9) | 1 (33.3) | 0.47 |
Smoking (%) | 9 (14.5) | 9 (15.3) | 0 | 0.74 |
Index event | ||||
Ischaemic stroke (%) | 44 (71.0) | 42 (71.2) | 2 (66.7) | 0.87 |
TIA (%) | 18 (29.0) | 17 (28.8) | 1 (33.3) | 0.87 |
Thrombolysis (%) | 4 (6.5) | 4 (6.8) | 0 | 0.64 |
Length of stay, days | 1 [1,3] (0–60) | 1 [0,3] (0–60) | 2 [−] (1-7) | 0.25 |
At recruitment | ||||
Time from index event, days | 49 [35,75] (1–285) | 52 [36,76] (1–285) | 1 [−] (1–22) | 0.006 |
mRS | 0 [0,1] | 0 [0,1] | 0 [−] | 0.89 |
On clopidogrel (%) | 62 (100) | 59 (100) | 3 (100) | – |
Time on clopidogrel, days | 50 [35, 76] (8–1878) | 48 [35, 69] (8–1878) | 313 [−] (8–962) | 0.41 |
On aspirin (%) | 3 (4.8) | 0 | 3 (100) | – |
Treated hypertension (%) | 43 (69.4) | 40 (67.8) | 3 (100) | 0.24 |
Treated hypercholesterolaemia (%) | 59 (95.2) | 56 (94.9) | 3 (100) | 0.69 |
Proton pump inhibitor (%) | 19 (30.6) | 17 (28.8) | 2 (66.7) | 0.17 |
Systolic BP, mm Hg | 135.7 (19.5) | 134.9 (19.3) | 150.0 (22.5) | 0.21 |
Diastolic BP, mm Hg | 76.3 (13.5) | 76.6 (13.7) | 71.7 (7.8) | 0.26 |
Bleeding history on antiplatelet(s) | ||||
Minor bleeding (%) | 17 (27.4) | 17 (28.8) | 0 | 0.28 |
Major bleeding (%) | 0 | 0 | 0 | – |
Data are number (%), mean (SD), median [IQR], (min–max); comparison between clopidogrel versus aspirin+clopidogrel groups by χ2 test, Kruskal-Wallis test or one-way analysis of variance.
Sixty-three participants recruited but 1 had no data collected.
BP, blood pressure; IHD, ischaemic heart disease; mRS, modified Rankin Scale; TIA, transient ischaemic attack.