Table 1

Baseline characteristics of participants

AllClopidogrel onlyAspirin+clopidogrelP value
n (%)62 (100.0)59 (95.2)3 (4.8)
Male (%)33 (53.2)33 (55.9)00.058
Age, years63.7 (13.7)63.0 (13.5)78.0 (8.9)0.06
Preindex event
 Stroke (%)9 (14.5)8 (13.6)1 (33.3)0.34
 TIA (%)8 (12.9)6 (10.2)2 (66.7)0.004
 IHD (%)6 (9.7)5 (8.5)1 (33.3)0.16
 Diabetes (%)11 (17.7)10 (16.9)1 (33.3)0.47
 Smoking (%)9 (14.5)9 (15.3)00.74
Index event
 Ischaemic stroke (%)44 (71.0)42 (71.2)2 (66.7)0.87
 TIA (%)18 (29.0)17 (28.8)1 (33.3)0.87
 Thrombolysis (%)4 (6.5)4 (6.8)00.64
 Length of stay, days1 [1,3] (0–60)1 [0,3] (0–60)2 [−] (1-7)0.25
At recruitment
 Time from index event, days49 [35,75] (1–285)52 [36,76] (1–285)1 [−] (1–22)0.006
 mRS0 [0,1]0 [0,1]0 [−]0.89
 On clopidogrel (%)62 (100)59 (100)3 (100)
 Time on clopidogrel, days50 [35, 76] (8–1878)48 [35, 69] (8–1878)313 [−] (8–962)0.41
 On aspirin (%)3 (4.8)03 (100)
 Treated hypertension (%)43 (69.4)40 (67.8)3 (100)0.24
 Treated hypercholesterolaemia (%)59 (95.2)56 (94.9)3 (100)0.69
 Proton pump inhibitor (%)19 (30.6)17 (28.8)2 (66.7)0.17
 Systolic BP, mm Hg135.7 (19.5)134.9 (19.3)150.0 (22.5)0.21
 Diastolic BP, mm Hg76.3 (13.5)76.6 (13.7)71.7 (7.8)0.26
Bleeding history on antiplatelet(s)
 Minor bleeding (%)17 (27.4)17 (28.8)00.28
 Major bleeding (%)000
  • Data are number (%), mean (SD), median [IQR], (min–max); comparison between clopidogrel versus aspirin+clopidogrel groups by χ2 test, Kruskal-Wallis test or one-way analysis of variance.

  • Sixty-three participants recruited but 1 had no data collected.

  • BP, blood pressure; IHD, ischaemic heart disease; mRS, modified Rankin Scale; TIA, transient ischaemic attack.