Baseline medical history and clinical characteristics of ICONS patients
| Baseline variables | All patients (N (%)) n=2625 | AIS (N (%)) n=2432 | TIA (N (%)) n=193 | P value |
| Medical history | ||||
| Diabetes | 599 (22.82) | 562 (23.11) | 37 (19.17) | 0.21 |
| Hypertension | 1642 (62.55) | 1530 (62.91) | 112 (58.03) | 0.18 |
| Lipid metabolism disorders | 259 (9.87) | 234 (9.62) | 25 (12.95) | 0.14 |
| Stroke history | 581 (22.13) | 534 (21.96) | 47 (24.35) | 0.44 |
| Cerebral infarction | 555 (21.14) | 509 (20.93) | 46 (23.83) | 0.34 |
| Intracranial cerebral haemorrhage | 35 (1.33) | 32 (1.32) | 3 (1.55) | 1.00 |
| Subarachnoid haemorrhage | 5 (0.19) | 4 (0.16) | 1 (0.52) | 0.32 |
| Transient ischaemic attack | 88 (3.35) | 64 (2.63) | 24 (12.44) | 0.001 |
| Heart disease | 356 (13.56) | 327 (13.45) | 29 (15.03) | 0.54 |
| Coronary heart disease | 296 (11.28) | 270 (11.10) | 26 (13.47) | 0.32 |
| Heart failure | 9 (0.34) | 9 (0.37) | 0 (0.00) | 1.00 |
| Atrial fibrillation | 76 (2.90) | 72 (2.96) | 4 (2.07) | 0.48 |
| Others | 17 (0.65) | 15 (0.62) | 2 (1.04) | 0.82 |
| Carotid artery stenosis | 18 (0.69) | 15 (0.62) | 3 (1.55) | 0.13 |
| Epilepsy | 7 (0.27) | 7 (0.29) | 0 (0.00) | 1.00 |
| Sleep apnoea | 34 (1.30) | 29 (1.19) | 5 (2.59) | 0.098 |
| Median time from symptom onset to enrolment (day) | 1 (0–2) | 1 (0–2) | 0 (0–1) | 0.031 |
| Median NIHSS score (IQR) | 3 (1–5) | 3 (1–5) | 0 (0–1) | 0.001 |
ICONS, Impairment of CognitiON and Sleep after acute ischemic stroke or transient ischemic attack in Chinese patients; NIHSS, National Institutes of Health Stroke Scale.