Secondary efficacy outcomes among the four groups
| Variables | Time (days) | Control n=94 | Low-dose n=97 | Medium-dose n=98 | High-dose n=96 | P value |
| NIHSS score ≤1, n (%) | 14 | 27 (28.72) | 20 (20.62) | 20 (20.41) | 21 (21.88) | 0.4975 |
| 30 | 32 (35.16) | 35 (36.46) | 36 (38.30) | 37 (38.95) | 0.9505 | |
| 90 | 49 (54.44) | 49 (51.04) | 51 (54.26) | 54 (58.06) | 0.8180 | |
| BI score ≥95, n (%) | 14 | 40 (42.55) | 43 (44.79) | 41 (42.27) | 44 (45.83) | 0.9514 |
| 30 | 50 (54.35) | 48 (50.00) | 56 (59.57) | 58 (61.05) | 0.3994 | |
| 90 | 66 (71.74) | 61 (63.54) | 68 (71.58) | 63 (67.02) | 0.5672 | |
| MoCA, mean±SD | 14 | 21.29±6.46 | 20.54±6.35 | 22.07±6.36 | 20.69±7.20 | 0.3325 |
| 30 | 23.31±5.75 | 22.52±6.35 | 23.00±6.34 | 22.56±6.80 | 0.8773 | |
| 90 | 23.99±5.68 | 23.67±5.37 | 23.53±6.84 | 22.56±6.80 | 0.7897 | |
| SIS, mean±SD | 90 | 635.48±141.91 | 618.50±152.51 | 637.52±143.67 | 623.68±159.71 | 0.8230 |
BI, Barthel Index; MoCA, Montreal Cognitive Assessment; NIHSS, National Institutes of Health Stroke Scale; SIS, Stroke Impact Scale.