Sensitivity analysis of the differential systolic and diastolic pressures (ie, pressure in the lenticulostriate vessels minus pressure in the posterior parietal vessels) with respect to modification of several model parameters
Variation of SBP/DBP (%) | |||
Model parameters | Feeding artery | 190 and 210 μm arterioles | 30 and 50 μm arterioles |
ΔRo=−5% | −18.6/–13.0 | −17.9/–11.9 | −16.9/–10.3 |
ΔRo=−15% | 23.5/12.9 | 21.8/10.8 | 19.9/8.2 |
Δh=+25% | −4.9/0.5 | −3.5/2.0 | −2.0/3.4 |
Δh=+75% | 4.4/–3.1 | 3.3/–4.1 | 2.2/–5.0 |
ΔRW=+30% | 2.9/–6.0 | 0.5/–8.7 | −2.9/–12.0 |
ΔRW=+90% | −2.8/–1.9 | −2.0/–0.4 | 0.5/3.2 |
ΔCW=−10% | 0.0/–0.2 | −0.1/–0.1 | −0.1/–0.1 |
ΔCW=−40% | 0.0/0.2 | 0.1/0.1 | 0.1/0.1 |
Percentages are computed with respect to the differential pressure in the hypertensive scenario.
ΔRW, change in peripheral resistance; ΔCW, change in network compliance; *ΔRo, change in lumen radius; Δh change in arterial wall thickness.