PT  - JOURNAL ARTICLE
AU  - Yang, Xiaoxia
AU  - Tian, De-Cai
AU  - He, Wenyan
AU  - Lv, Wei
AU  - Fan, Junwan
AU  - Li, Haowen
AU  - Jin, Wei-Na
AU  - Meng, Xia
TI  - Cellular and molecular imaging for stem cell tracking in neurological diseases
AID  - 10.1136/svn-2020-000408
DP  - 2021 Mar 01
TA  - Stroke and Vascular Neurology
PG  - 121--127
VI  - 6
IP  - 1
4099  - http://svn.bmj.com/content/6/1/121.short
4100  - http://svn.bmj.com/content/6/1/121.full
SO  - Stroke Vasc Neurol2021 Mar 01; 6
AB  - Stem cells (SCs) are cells with strong proliferation ability, multilineage differentiation potential and self-renewal capacity. SC transplantation represents an important therapeutic advancement for the treatment strategy of neurological diseases, both in the preclinical experimental and clinical settings. Innovative and breakthrough SC labelling and tracking technologies are widely used to monitor the distribution and viability of transplanted cells non-invasively and longitudinally. Here we summarised the research progress of the main tracers, labelling methods and imaging technologies involved in current SC tracking technologies for various neurological diseases. Finally, the applications, challenges and unresolved problems of current SC tracing technologies were discussed.