PT  - JOURNAL ARTICLE
AU  - Zhu, Zhu
AU  - Yu, Wengui
TI  - Update in the treatment of extracranial atherosclerotic disease for stroke prevention
AID  - 10.1136/svn-2019-000261
DP  - 2020 Mar 01
TA  - Stroke and Vascular Neurology
PG  - 65--70
VI  - 5
IP  - 1
4099  - http://svn.bmj.com/content/5/1/65.short
4100  - http://svn.bmj.com/content/5/1/65.full
SO  - Stroke Vasc Neurol2020 Mar 01; 5
AB  - Stroke is a leading cause of adult mortality and disability worldwide. Extracranial atherosclerotic disease (ECAD), primarily, carotid artery stenosis, accounts for approximately 18%–25% of ischaemic stroke. Recent advances in neuroimaging, medical therapy and interventional management have led to A significant reduction of stroke from carotid artery stenosis. The current treatment of ECAD includes optimal medical therapy, carotid endarterectomy (CEA) and carotid artery stenting (CAS). The selection of treatments depends on symptomatic status, severity of stenosis, individual factors, efficacy and risk of complications. The aim of this paper is to review current evidence and guidelines on the management of carotid artery stenosis, including the comparison of medical and interventional therapy (CAS and CEA), as well as future directions.