RT Journal Article
SR Electronic
T1 The Third China National Stroke Registry (CNSR-III) for patients with acute ischaemic stroke or transient ischaemic attack: design, rationale and baseline patient characteristics
JF Stroke and Vascular Neurology
JO Stroke Vasc Neurol
FD BMJ Publishing Group Ltd
SP 158
OP 164
DO 10.1136/svn-2019-000242
VO 4
IS 3
A1 Wang, Yongjun
A1 Jing, Jing
A1 Meng, Xia
A1 Pan, Yuesong
A1 Wang, Yilong
A1 Zhao, Xingquan
A1 Lin, Jinxi
A1 Li, Wei
A1 Jiang, Yong
A1 Li, Zixiao
A1 Zhang, Xinmiao
A1 Yang, Xiaomeng
A1 Ji, Ruijun
A1 Wang, Chunjuan
A1 Wang, Zhimin
A1 Han, Xinsheng
A1 Wu, Songdi
A1 Jia, Zhengchang
A1 Chen, Yongming
A1 Li, Hao
YR 2019
UL http://svn.bmj.com/content/4/3/158.abstract
AB Background and purpose Stroke is the leading cause of mortality and disability in China. Precise aetiological classification, imaging and biological markers may predict the prognosis of stroke. The Third China National Stroke Registry (CNSR-III), a nationwide registry of ischaemic stroke or transient ischaemic attack (TIA) in China based on aetiology, imaging and biology markers, will be considered to clarify the pathogenesis and prognostic factors of ischaemic stroke.Methods Between August 2015 and March 2018, the CNSR-III recruited consecutive patients with ischaemic stroke or TIA from 201 hospitals that cover 22 provinces and four municipalities in China. Clinical data were collected prospectively using an electronic data capture system by face-to-face interviews. Patients were followed for clinical outcomes at 3 months, 6 months and 1–5 year annually. Brain imaging, including brain MRI and CT, were completed at baseline. Blood samples were collected and biomarkers were tested at baseline.Results A total of 15 166 stroke patients were enrolled, among which 31.7% patients were women with the average age of 62.2±11.3 years. Ischaemic stroke was predominant (93.3%, n=14 146) and 1020 (6.7%) TIAs were enrolled.Conclusions CNSR-III is a large scale nationwide registry in China. Data from this prospective registry may provide opportunity to evaluate imaging and biomarker prognostic determinants of stroke.