PT  - JOURNAL ARTICLE
AU  - Shen, Ling
AU  - Bai, Ying
AU  - Han, Bing
AU  - Yao, Honghong
TI  - Non-coding RNA and neuroinflammation: implications for the therapy of stroke
AID  - 10.1136/svn-2018-000206
DP  - 2019 Jun 01
TA  - Stroke and Vascular Neurology
PG  - 96--98
VI  - 4
IP  - 2
4099  - http://svn.bmj.com/content/4/2/96.short
4100  - http://svn.bmj.com/content/4/2/96.full
AB  - Stroke is the major leading cause of death and serious, long-term disability with major economic consequences. At present, the lack of rapid diagnostic, prognostic biomarkers and effective treatment methods are two major challenges facing stroke. Circular RNAs (circRNAs) are potential clinical biomarkers in central nervous system diseases. However, the potential role of circRNAs in neuroinflammation and neuron functional recovery in acute ischaemic stroke (AIS) remains largely unknown. This review aimed to give an overview of the function of circRNAs in AIS and summarise the latest achievements in this field.